Monday, October 21, 2013

About Dactinomycin

The Dactinomycin is a class of polypeptide antibiotics isolated from soil bacteria of the genus Streptomyces, of which the most significant is actinomycin D.It is primarily used as an investigative tool in cell biology to inhibit transcription. Dactinomycin does this by binding DNA at the transcription initiation complex and preventing elongation by RNA polymerase.

Friday, October 18, 2013

About Flumetasone

Flumetasone (usually as the pivalic acid ester flumetasone pivalate, trade name Locacorten or Locorten) is acorticosteroid for topical use. It is available in combination with clioquinol, under the trade name Locacorten-Vioform (i, for the treatment of otitis externaand otomycosis.

About Fluticasone propionate


 Fluticasone propionate is a corticosteroid derived fromfluticasone used to treat asthma and allergic rhinitis. It is also used to treat eosinophilic esophagitis.GlaxoSmithKline currently markets fluticasone propionate asFlovent (USA and Canada) and Flixotide (EU) for asthma, and as Flonase (USA and Canada), Flixonase (Australia, Brazil, EU, India, Israel, South Africa, and South Korea) and Pirinase (UK) for allergic rhinitis (hay fever), as well as a combination of fluticasone and salmeterol asAdvair (USA and Canada) or Seretide[1] (EU). In India it is also marketed by Intas under the trade name 'Ezicas'.

EzicasTeva markets fluticasone propionate as Nasofan in Italy. It is available asFluticone in India. It is also available as a cream (marketed as Cutivate orFlutivate) for the treatment of eczema and psoriasis. 
Fluticasone propionate is a synthetic trifluorinated glucocorticoid.

Thursday, October 17, 2013

About Azoxymethane

Azoxymethane is a carcinogenic and neurotoxic chemical compound used in biological research. It is the oxide of azomethane. Azoxymethane is particularly effective in inducing colon carcinomas.

CAS:25843-45-2
Molecular Formula:C2H6N2O
Molecular Weight:74.08g/mol

About Burgess reagent

Burgess reagent is used to convert secondary and tertiary alcohol with an adjacent proton into alkenes. The reagent is soluble in common organic solvents and alcohol dehydration takes place with syn elimination. The Burgess reagent is a carbamate and a so-called inner salt.

Wednesday, October 16, 2013

About Eplerenone

Eplerenone is an aldosterone antagonist used as an adjunct in the management of chronic heart failure.Eplerenone  is specifically indicated for the reduction of risk of cardiovascular death in patients with heart failure and left ventricular dysfunction within 3–14 days of an acute myocardial infarction, in combination with standard therapies and as treatment against hypertension.

About Dutasteride

Dutasteride (brand name Avodart) is a 5-alpha-reductase inhibitor that inhibits the conversion of testosterone into dihydrotestosterone (DHT).Dutasteride  belongs to a class of drugs called 5-alpha-reductase inhibitors, which block the action of the 5-alpha-reductase enzymes that convert testosterone into dihydrotestosterone (DHT). Finasteride, which is also approved for the treatment of benign prostatic hyperplasia (BPH), in addition to the treatment of male pattern baldness (MPB), belongs to this class of drugs.