Friday, April 27, 2012
The introduction of PyAOP
Phosphonium derivatives of HOAt such as PyAOP are advantageous for the solid-phase alertness of a ambit of peptides that cover those accumulation hindered amino acids, difficult abbreviate sequences, and circadian peptides. An advantage about to uronium salts is that balance PyAOP does not abide the adverse side-reaction at the amino abuttals which blocks added alternation assembly.Phosphonium derivatives of HOAt such as PyAOP are advantageous for the solid-phase alertness of a ambit of peptides that cover those accumulation hindered amino acids, difficult abbreviate sequences, and circadian peptides. An advantage about to uronium salts is that balance PyAOP does not abide the adverse side-reaction at the amino abuttals which blocks added alternation assembly.
Product Name: (7-Azabenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate, PyAOP
CAS No: 156311-83-0
Molecular Formula: C17H27F6N7OP2
Molecular Weight: 521.38
Appearance: White to fair crumb
Puriy: 99%min.
Melting Point: 163-168 C
Loss on Drying: 0.5% max.
Heavy Metals: 20 ppm max.
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The information of Concentrated Antibacterial Solution
Concentrated Antibacterial Solution
Characteristics
1. High able and ample spectrum antibacteria: the antibacterial aftereffect to Escherichia coli, Staphylococcus aureuss, Salmonella aertrycke and added accepted adverse bacilli are all college than 99%.
2. Advantageous and safety: mice articulate toxicity LD505000 mg / Kg; the affliction tests announce that it has no affliction to eye and derma of the beginning rabbit.
3. No anaphylaxis and abeyant ancillary effects, with no formaldehyde and abundant metals.
4. Good dispensability: can be well-mixed in baptize and added media, broadcast evenly.
5. Abiding anti-bacterial effect: antibacterial capacity can acknowledge with bolt cilia atomic to anatomy a actinic aggregate by the coupling agent, biting abettor and added acknowledging chemicals. As-treated articles has accomplished abrasion attrition that the antibacterial aftereffect is still up added than 95 percent by afterwards 50 times’ washing.
6. No access to the whiteness, color, tenacity, duke feel and air permeability of textile.
Concentrated Antibacterial Solution Applications
1.Used in the germ-free accomplishment of fibers and non-woven fabrics like cotton, wool, silk, linen, velvet, terylene, chinlon, spun-bonded cilia and their attenuated fabrics, giving them abiding anti-bacterial, anti-mildew, the capability of deodorant. Can be acclimated for the assembly of bed sheets, underwear, towels, socks, carpets, non-woven fabrics, shoes, adorning cloth, air filtration abstracts with antibacterial, deodorant, anti-mildew function.
2. Acclimated as anti-bacterial and anti-mildew abettor in accessories for accessible places, advantageous soap, face cleaner, shampoo, germ-free napkins, leather, and etc.
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The decription of All black components CS5A
All black components CS5A
All black components CS5A introduction:Solar energy battery components (also called solar panels) is the core part of the solar power system, solar power system, the highest value. Its role is to convert solar energy into electrical energy, or sent is stored in batteries, or promote the work load. The quality and cost of solar panels will directly determine the quality and cost of the entire system.
The core of the solar modules – solar cells
(1) the photoelectric conversion efficiency of silicon solar cells in monocrystalline silicon solar cells for about 17 percent, the highest 24%, which is all kinds of solar cells, photoelectric conversion efficiency, but the production costs, resulting in it can not be a large number of extensive and widespread use. The general use of silicon tempered glass and waterproof resin encapsulated, so durable, manufacturers generally provide 25 years of quality assurance.
(2) The production process for polysilicon solar cells, polycrystalline silicon solar cells with silicon solar cells, photoelectric conversion efficiency of polycrystalline silicon solar cells will have to reduce the number of the photoelectric conversion efficiency of about 15% (Suntech in Europe, Intersolar in introduced in the 2011 exhibition a to named STP250S-20/Wd + ” BlackPearl ” (black Pearl), a new generation of high efficiency PV module conversion efficiency of 15.2%.) Cheaper than monocrystalline silicon solar cells in terms of production costs, some simple materials, to save power consumption, the total production costs are lower, so get a lot of development. In addition, the polycrystalline silicon solar battery life is shorter than the monocrystalline silicon solar cells. From the cost monocrystalline silicon solar cells is also slightly better.
(3) amorphous silicon solar cells, amorphous silicon solar cells is the new thin film solar cells in 1976, it is completely different from the production of monocrystalline and polycrystalline silicon solar cells, greatly simplify the process, very little silicon consumption, lower power consumption, its main advantage is in low light conditions can also generate electricity. But the main problems of amorphous silicon solar cells is the photoelectric conversion efficiency is low, the current international advanced level for about 10%, and is not stable enough, with time, the conversion efficiency of decay.
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The information of All black components CS5A-1
All black components CS5A-1
All black components CS5A-1 decription:The solar modules (also called solar panels) is the core part of the solar power system, solar power system, the highest value. Its role is to convert solar energy into electrical energy, or sent is stored in batteries, or promote the work load. The quality and cost of solar panels will directly determine the quality and cost of the entire system.
Basic requirements of solar modules
1, can provide sufficient mechanical strength, able to withstand the transportation, installation and use of impact occurred during the stress generated by vibration, able to withstand the force of the living hail click to make solar modules;
2, has a good seal can windproof, waterproof, cut off from the corrosion of the atmospheric conditions on solar cells;
3, has a good electrical insulation properties;
4, UV resistance;
5, the operating voltage and the output power according to different requirements for design, can provide a variety of wiring to meet the different voltage, current and power output requirements;
6, loss of efficiency due to the solar cells in series and parallel combinations;
7, connecting reliable solar cells;
8, long working life, the solar modules to be able to use more than 20 years under natural conditions;
9, under the aforementioned conditions are met, the package costs as low as possible.
The core of the solar modules – solar cells
(1) the photoelectric conversion efficiency of silicon solar cells in monocrystalline silicon solar cells for about 17 percent, the highest 24%, which is all kinds of solar cells, photoelectric conversion efficiency, but the production costs, resulting in it can not be a large number of extensive and widespread use. The general use of silicon tempered glass and waterproof resin encapsulated, so durable, manufacturers generally provide 25 years of quality assurance.
(2) The production process for polysilicon solar cells, polycrystalline silicon solar cells with silicon solar cells, photoelectric conversion efficiency of polycrystalline silicon solar cells will have to reduce the number of the photoelectric conversion efficiency of about 15% (Suntech in Europe, Intersolar in introduced in the 2011 exhibition a to named STP250S-20/Wd + ” BlackPearl ” (Black Pearl), a new generation of high efficiency PV module conversion efficiency of 15.2%.) Cheaper than monocrystalline silicon solar cells in terms of production costs, some simple materials, to save power consumption, the total production costs are lower, so get a lot of development. In addition, the polycrystalline silicon solar battery life is shorter than the monocrystalline silicon solar cells. From the cost monocrystalline silicon solar cells is also slightly better.
(3) of amorphous silicon solar cells of amorphous silicon solar cell is 1976 the new thin film solar cells, it is completely different from the production of monocrystalline and polycrystalline silicon solar cells, greatly simplify the process, very little silicon consumption, lower power consumption, its main advantage is in low light conditions can also generate electricity. But the main problems of amorphous silicon solar cells is the photoelectric conversion efficiency is low, the current international advanced level for about 10%, and is not stable enough, with time, the conversion efficiency of decay.
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Thursday, April 26, 2012
The Characteristics of MMT
Degradation of mono-methyl terephthalate (MMT) by Pasteurella multocida Sa in the attendance of booze (a) and booze (b). The metabolites were detected and quantified by HPLC. Vertical confined are accepted aberration from three absolute experiments.Hydrolysis of dimethyl terephthalate (DMT) to aftermath terephthalic acerbic (TPA) was advised application a accumulation reactor. Zink acetate was acclimated as a agitator to advance the acknowledgment rate. We begin that the acknowledgment consists of two reactions: from DMT to address methyl terephthalate (MMT) and again MMT to TPA. The aboriginal acknowledgment is almost fast and irreversible while the additional acknowledgment is almost apathetic and reversible. A active calm connected for the additional acknowledgment decreases with acknowledgment temperature. A active archetypal consisting of the two reactions for the hydrolysis adapted able-bodied with the beginning data.Biodegradation of DMT was apparent to yield abode as a alternation of consecutive accomplish involving the hydrolysis of two ester linkages amid the carboxyl groups of the terephthalate and the methyl side-chain initially to aftermath mono-methyl terephthalate (MMT) and again terephthalic acerbic (TA), respectively. However, with booze as the accustomed solvent, there was a accumulation of one metabolite ahead not observed. The two metabolites were characterized by top performance-liquid chromatography-electron ionization accumulation spectrometry as MMT and mono-ethyl terephthalate (MET), suggesting the actuality of an another biochemical alleyway in the abasement of DMT by P. multocida Sa. Since the attendance of MMT and booze in ability inoculated with P. multocida Sa was prerequisites for the accumulation of MET, biologically advised trans-esterification was proposed as a apparatus for the atypical biochemical action observed.
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Wednesday, April 25, 2012
The presentation of HOBt
1 - hydroxy benzotriazole (HOBT), ≥ 99% (HPLC)
Chinese name: 1 - hydroxy benzotriazole (HOBT), ≥ 99% (HPLC)
English name: NHydroxybenzotrizole
Synonyms: HOBT123Benzotriazol1ol.
Purity: ≥ 99%
CAS No.: 2592-95-2
Molecular formula: C6H5N3O
Molecular weight: 135.13 Performance description
Characters: white to off-white crystals
Physical parameters: melting point: 156 ~ 159 ° C (dec.)
Specifications
Purity: ≥ 99% (HPLC)
Loss on drying: ≤ 0.5%
Heavy metals: ≤ 20ppm
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Use instructions
DCC as a condensing agent in peptide synthesis inhibition racemic
Storage Transport: a cool dry place based on the amino components of a single N-alpha protected amino acids repeatedly added to the growth, synthesis of a step-by-step manner, usually from a synthesis of the C-terminal amino acid chain, followed by a single amino acid connected via the DCC, mixed carbon anhydride, or N-carboxy anhydride method. The Carbodiimide methods to connect the N-and C-protected amino acids using DCC coupling agent. Important connection reagents to Promote N to protect the freedom of amino acid carbon-based and C-protected amino acids, amino shrink, the formation of the peptide chain, while the output of N, N? / FONT>-dyaylcohercylurea byproduct. This method, however, because it led to the racemic side effects, or 5 (4H)-oxaylones and N-acylurea affected the formation of alkali exist. Fascinatingly, it is that these side effects can be minimized, if not completely eliminate. Method is to add the connection catalyst as HoSu or HoBT In addition, this method can be used for the synthesis of N-protected amino acids activated ester derivatives. Active ester in turn generated by spontaneous reaction with any other C-protected amino acids or peptides to form a new peptide.
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Friday, April 20, 2012
The decription of All black components CS5A-2
All black components CS5A-2
All black components CS5A-2 introduction:The solar modules (also called solar panels) is the core part of the solar power system, solar power system, the highest value. Its role is to convert solar energy into electrical energy, or sent is stored in batteries, or promote the work load. The quality and cost of solar panels will directly determine the quality and cost of the entire system.
The core of the solar modules – solar cells
(1) the photoelectric conversion efficiency of silicon solar cells in monocrystalline silicon solar cells for about 17 percent, the highest 24%, which is all kinds of solar cells, photoelectric conversion efficiency, but the production costs, resulting in it can not be a large number of extensive and widespread use. The general use of silicon tempered glass and waterproof resin encapsulated, so durable, manufacturers generally provide 25 years of quality assurance.
(2) The production process for polysilicon solar cells, polycrystalline silicon solar cells with silicon solar cells, photoelectric conversion efficiency of polycrystalline silicon solar cells will have to reduce the number of the photoelectric conversion efficiency of about 15% (Suntech in Europe, Intersolar in introduced in the 2011 exhibition a to named STP250S-20/Wd + ” BlackPearl ” (black Pearl), a new generation of high efficiency PV module conversion efficiency of 15.2%.) Cheaper than monocrystalline silicon solar cells in terms of production costs, some simple materials, to save power consumption, the total production costs are lower, so get a lot of development. In addition, the polycrystalline silicon solar battery life is shorter than the monocrystalline silicon solar cells. From the cost monocrystalline silicon solar cells is also slightly better.
(3) amorphous silicon solar cells, amorphous silicon solar cells is the new thin film solar cells in 1976, it is completely different from the production of monocrystalline and polycrystalline silicon solar cells, greatly simplify the process, very little silicon consumption, lower power consumption, its main advantage is in low light conditions can also generate electricity. But the main problems of amorphous silicon solar cells is the photoelectric conversion efficiency is low, the current international advanced level for about 10%, and is not stable enough, with time, the conversion efficiency of decay.
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The function of PyBOP
PyBOP (benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent acclimated in solid appearance peptide synthesis. It is acclimated as a acting for the BOP reagent, appropriately alienated the accumulation of the baleful ancillary artefact HMPA.PyBOP is the BOP coupling reagent analogues, but it will not anatomy the by-product, baleful HMPA.Synthesis of Benzotriazolyloxy tris [dimethyl-amino] phosphonium hexafluorophosphate (BOP) and Benzotriazolyloxy tris [pyrrolidino] phosphonium hexafluorophosphate (PyBOP), application triphosgene and hydroxybenzotriazole.
Endothiopeptides accept been acquired by application PyBOP® answer coupling amid Fmoc-protected amino monothioacids and amino acerbic or peptide esters. The adequate endothiopeptides (Fmoc-Gly-ψ(CSNH)-Phe-OEt, Fmoc-Tyr(But)-ψ(CSNH)-Gly-Gly-Phe-Leu-OBut and Fmoc-Gln(Trt)-ψ(CSNH)-Phe-OEt) were formed (55, 45 and 37% yield) in admixture with the agnate oxopeptides, from which they were calmly afar chromatographically. Preliminary racemisation studies announce that articles of top optical abstention are obtained. The apparatus for endothiopeptide accumulation is briefly discussed.Pyrrolidide derivatives are empiric as exceptionable by-products from apathetic reactions of activated carboxylates with nucleophilic amines, as advised by phosphonium alkali coupling reagents (PyAOP, PyBOP, PyBroP). This ancillary acknowledgment is attributed to the attendance of baby amounts (e.g., 0.5%, w/w) of pyrrolidine as a contaminant to bartering phosphonium salts, and does not action if the reagents are crystallized afore their use in coupling reactions.
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Thursday, April 19, 2012
The decription of All black components CS5A-3
All black components CS5A-3 introduction:The solar modules (also called
solar panels) is the core part of the solar power system, solar power system,
the highest value. Its role is to convert solar energy into electrical energy,
or sent is stored in batteries, or promote the work load. The quality and cost
of solar panels will directly determine the quality and cost of the entire
system.
The core of the solar modules – solar cells
(1) the photoelectric conversion efficiency of silicon solar cells in monocrystalline silicon solar cells for about 17 percent, the highest 24%, which is all kinds of solar cells, photoelectric conversion efficiency, but the production costs, resulting in it can not be a large number of extensive and widespread use. The general use of silicon tempered glass and waterproof resin encapsulated, so durable, manufacturers generally provide 25 years of quality assurance.
(2) The production process for polysilicon solar cells, polycrystalline silicon solar cells with silicon solar cells, photoelectric conversion efficiency of polycrystalline silicon solar cells will have to reduce the number of the photoelectric conversion efficiency of about 15% (Suntech in Europe, Intersolar in introduced in the 2011 exhibition a to named STP250S-20/Wd + ” BlackPearl ” (black Pearl), a new generation of high efficiency PV module conversion efficiency of 15.2%.) Cheaper than monocrystalline silicon solar cells in terms of production costs, some simple materials, to save power consumption, the total production costs are lower, so get a lot of development. In addition, the polycrystalline silicon solar battery life is shorter than the monocrystalline silicon solar cells. From the cost monocrystalline silicon solar cells is also slightly better.
(3) amorphous silicon solar cells, amorphous silicon solar cells is the new thin film solar cells in 1976, it is completely different from the production of monocrystalline and polycrystalline silicon solar cells, greatly simplify the process, very little silicon consumption, lower power consumption, its main advantage is in low light conditions can also generate electricity. But the main problems of amorphous silicon solar cells is the photoelectric conversion efficiency is low, the current international advanced level for about 10%, and is not stable enough, with time, the conversion efficiency of decay.
(1) the photoelectric conversion efficiency of silicon solar cells in monocrystalline silicon solar cells for about 17 percent, the highest 24%, which is all kinds of solar cells, photoelectric conversion efficiency, but the production costs, resulting in it can not be a large number of extensive and widespread use. The general use of silicon tempered glass and waterproof resin encapsulated, so durable, manufacturers generally provide 25 years of quality assurance.
(2) The production process for polysilicon solar cells, polycrystalline silicon solar cells with silicon solar cells, photoelectric conversion efficiency of polycrystalline silicon solar cells will have to reduce the number of the photoelectric conversion efficiency of about 15% (Suntech in Europe, Intersolar in introduced in the 2011 exhibition a to named STP250S-20/Wd + ” BlackPearl ” (black Pearl), a new generation of high efficiency PV module conversion efficiency of 15.2%.) Cheaper than monocrystalline silicon solar cells in terms of production costs, some simple materials, to save power consumption, the total production costs are lower, so get a lot of development. In addition, the polycrystalline silicon solar battery life is shorter than the monocrystalline silicon solar cells. From the cost monocrystalline silicon solar cells is also slightly better.
(3) amorphous silicon solar cells, amorphous silicon solar cells is the new thin film solar cells in 1976, it is completely different from the production of monocrystalline and polycrystalline silicon solar cells, greatly simplify the process, very little silicon consumption, lower power consumption, its main advantage is in low light conditions can also generate electricity. But the main problems of amorphous silicon solar cells is the photoelectric conversion efficiency is low, the current international advanced level for about 10%, and is not stable enough, with time, the conversion efficiency of decay.
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black components CS5A-3 for sale
The presentation of sulfo-NHS
NHS and Sulfo-NHS are acclimated to adapt amine-reactive esters of carboxylate groups for actinic labeling, crosslinking and
solid-phase apathy applications. Carboxylates (-COOH) may be reacted to NHS or Sulfo-NHS in the attendance of a
carbodiimide such as EDC (Product No. 22980), consistent in a semi-stable NHS or Sulfo-NHS ester, which may again be
reacted with primary amines (-NH2) to anatomy amide crosslinks (Figure 1). Although NHS or Sulfo-NHS is not appropriate for
carbodiimide reactions, their use abundantly enhances coupling efficiency. Furthermore, application NHS or Sulfo-NHS makes it
possible to accomplish a two-step reaction.
Both NHS and Sulfo-NHS are acrid in aqueous and amoebic solvents. Activation with NHS, however, decreases watersolubility of the adapted carboxylate molecule, while activation with Sulfo-NHS preserves or increases water-solubility of
the adapted molecule, by advantage of the answerable sulfonate group. Although able NHS or Sulfo-NHS esters are sufficiently abiding to action in a two-step acknowledgment scheme, both groups will hydrolyze aural hours or minutes, depending on water-content and pH of the acknowledgment solution. (NHS esters accept a half-life of 4-5 hours at pH 7, 1 hour at pH 8 and alone
10 account at pH 8.6.)
Procedures for abstraction and dehydration can be developed to adapt abiding NHS-activated molecules,
but best after-effects are acquired if NHS-activated molecules are acclimated promptly for acknowledgment to the amine-containing targets.
The activation acknowledgment with EDC and Sulfo-NHS is a lot of able at pH 4.5-7.2, and EDC reactions are generally performed in
MES absorber (Product No. 28390) at pH 4.7-6.0. Acknowledgment of Sulfo-NHS-activated molecules with primary amines is a lot of
efficient at pH 7-8, and Sulfo-NHS-ester reactions are usually performed in phosphate-buffered acrid (PBS) at pH 7.2-7.5.
For best after-effects in two-step reactions, accomplish the aboriginal acknowledgment in MES absorber (or added non-amine, non-carboxylate buffer)
at pH 5-6, again accession the pH to 7.2-7.5 with phosphate absorber (or added non-amine buffer) anon afore acknowledgment to the
amine-containing molecule.
EDC reactions can be quenched with 2-mercaptoethanol (2-ME), or the balance reagent can simply be removed (as able-bodied as the acknowledgment pH adjusted) by buffer-exchange with a desalting cavalcade (see Related Pierce
Products). For added altercation of EDC/NHS chemistry, including abounding archetype applications and protocols, argue the
book by Hermanson (see Related Pierce Products).
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Wednesday, April 18, 2012
The information of Master Batch of Antibacterial Plastics
Master Batch of Antibacterial Plastics decription:The masterbatch is
composed by the excess of chemical additives, carrier resin and dispersant.
Masterbatch is a uniform set out the extraordinary amount of pigment (dye) is
attached to the resin obtained aggregates.
Masterbatch mainly constitute
Pigments: generally divided organic pigments such as phthalocyanine green, etc.; inorganic pigments such as red iron oxide, titanium dioxide; dyes, such as restore pink, Disperse Orange. Polyolefin, PVC masterbatch is used in pigments, generally said that the dye can not be used for polyolefin coloration, otherwise it will cause severe migration.
Dispersant: wetting the surface of the pigment, the pigment further dispersed and stable in the resin, and must have good compatibility with the resin does not affect the quality of the coloring products. Polyolefin masterbatch dispersants are generally low molecular weight polyethylene wax or stearic acid zinc. Engineering plastics masterbatch dispersants commonly used polar low molecular weight polyethylene wax, magnesium stearate, stearic calcium.
Third, the carrier resin: the pigment evenly distributed and masterbatch granular. Select the carrier to be considered compatible with the colored resin, but also consider the masterbatch should be well-dispersed, and therefore the carrier mobility should be higher than the colored resin, the coloring does not affect product quality. Such as the use of larger melt index of similar polymers, masterbatch melt index higher than with the polymer, in order to ensure that the final products of the same color. PE, PP masterbatch select LDPE (low density polyethylene) resin as a carrier, PS, ABS masterbatch modified PS carrier.
Masterbatch mainly constitute
Pigments: generally divided organic pigments such as phthalocyanine green, etc.; inorganic pigments such as red iron oxide, titanium dioxide; dyes, such as restore pink, Disperse Orange. Polyolefin, PVC masterbatch is used in pigments, generally said that the dye can not be used for polyolefin coloration, otherwise it will cause severe migration.
Dispersant: wetting the surface of the pigment, the pigment further dispersed and stable in the resin, and must have good compatibility with the resin does not affect the quality of the coloring products. Polyolefin masterbatch dispersants are generally low molecular weight polyethylene wax or stearic acid zinc. Engineering plastics masterbatch dispersants commonly used polar low molecular weight polyethylene wax, magnesium stearate, stearic calcium.
Third, the carrier resin: the pigment evenly distributed and masterbatch granular. Select the carrier to be considered compatible with the colored resin, but also consider the masterbatch should be well-dispersed, and therefore the carrier mobility should be higher than the colored resin, the coloring does not affect product quality. Such as the use of larger melt index of similar polymers, masterbatch melt index higher than with the polymer, in order to ensure that the final products of the same color. PE, PP masterbatch select LDPE (low density polyethylene) resin as a carrier, PS, ABS masterbatch modified PS carrier.
The introduction of TBTU
A new polymer-supported TBTU (P-TBTU) has been able from polystyrene-bound 1-hydroxybenzotriazole (P-HOBT) and acclimated calmly as a solid-supported reagent for peptide-coupling reactions, and is even able with wet solvents. The P-HOBT can be recovered by simple filtration and reused for the alertness of new P-TBTU.Bortezomib is a first-in-class ameliorative antineoplastic abettor acclimated for alleviative patients with assorted myeloma and crimson corpuscle lymphoma. In this cardboard we address an bigger adjustment for amalgam of the appellation admixture application a allied approach. TBTU was begin to calmly abolish racemization in the fragment condensation. In allegory with the aboriginal synthesis, the presented one is beneath by two steps, college in yield, and provides bigger atom economy.TBTU(O-(Benzotriazol-1-yl)-N,N,N',N'-tetra methyluronium tetrafluoroborate) is acclimated as a peptide coupling reagent.TBTU is an uronium alkali that acts as a awful able coupling reagent acclimated in peptide allure for a advanced array of peptide sequences, including the amalgam of some pharmaceutical peptides.TBTU is one of the a lot of accepted coupling reagents and additives acclimated in peptide chemistry.
It shows the two tautomeric forms of TBTU, of which anatomy I reacts with the carboxylate ion .TBTU as a coupling reagent. The top ability and affluence of artefact isolation, prompted us to investigate its use for the absolute acknowledgment of carboxylic acerbic derivatives and amines or phenylhydrazine for the amalgam of adapted amides and phenylhydrazides at allowance temperature (Schemes 2 and . Several carboxylic acids (benzoic acerbic derivatives, phenyl acetic acid, and a adequate amino acid) were readily adapted into the agnate amides in acceptable to top yields .
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Tuesday, April 17, 2012
The information of N-ZnO Antibacterial Agent
N-ZnO Antibacterial Agent
【Product name】n-ZnO Antibacterial Agent
【Abbr.】n-ZnOw
【Specification Model】AT-83-02
【Appearance】white or abreast white powder
【Chemical Composition】zinc oxide (ZnO), dopant, dispersing agent
【Characteristics】
1.High able and ample spectra for antibacterial property: the minimum inhibitory concentrations (MIC) for killing and inhibiting the bacilli such as Staphylococcus Aureus (ATCC 6538), Escherichia Coli (ATCC 25922) and Candida Albicans (ATCC 10231) are 55~440 PPM, fibbers absolute 1 wt% of the benumbed ZnO accept added than 99% ability for anti the mentioned bacteria.
2.Safety: The ethics of the median-lethal-dose (LD50) of the benumbed ZnO powders are added than 5000 mg/Kg, which adumbrated they were nonpoisonous, and the affliction tests announce that it has no affliction to eye and derma of the beginning rabbit.
3.The benumbed ZnO displays abiding for action and stability.
4.Ease of use: simple to be broadcast and acceptable behavior for processing.
5.Good water-resistant property: about baffling in water.
6.Heat resistance: the accomplished temperature for appliance and processing is 500 ℃
7.Diameter: beneath than 600 nm.
【Dosage】
1wt%~2wt% in the cast of resin.
【Instruction for use】
Mix cast abstracts with n-ZnO and added abetting agents and action as aboriginal production.
【Storage】
Keep closed in air-conditioned dry abode , carriage and accumulator according to non-dangerous goods.
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The information of T-ZnO Antibacterial Agent
T-ZnO Antibacterial Agent
Zinc oxide whisker antibacterial agent
【Product Name】 zinc oxide whisker antibacterial agent
【English name】 T-ZnO Antibacterial Agent
[Chemical abbreviation T-ZnOw
【Specification】 AT-83
Product appearance】 white or nearly white powder
[Chemical composition] zinc oxide (ZnO)
The main characteristics of 1. The use of cutting-edge nano-effect and good dispersion of the T-ZnOw through the control structure, lattice doped composite sensitization and other technical means to control its antibacterial and environmental purification of the active center, a high efficiency, broad-spectrum, long-lasting antibacterial. Two. Add 1% to the fiber and coating, 2% to substrate materials such as plastics and rubber, the harmful bacteria E. coli, Staphylococcus aureus, Salmonella and other common antibacterial rate of more than 99%. 3. Good use of security and non-irritating.
[Performance] Item Index Appearance white or nearly white powder needle length (μm) ≤ 30 spicules root diameter (μm) 0.5 ~ 2 minimum inhibitory concentration, MIC (PPM) ≤ 200 oral toxicity LD50 (mg / kg) ≥ 10 000 (nontoxic) irritating to eyes and skin irritating coefficient of thermal expansion (% / ° C) 4.0 × 10-6 heat resistance (° C) ≥ 500 ° C
The scope of application This product is widely used in plastics, fibers, coatings, paper, flooring, furniture, household appliances, clothing, textiles and other products to give these materials and products to the antibacterial function.
[Add the amount of paint, fiber 1 wt% of plastics, building materials, rubber, 2 wt% of
Storage method in a cool dry place seal preservation, transportation and storage of non-dangerous goods.
[Note] recommended to use before the first of the products 2 to 6 hours of drying temperature was controlled at 120 ℃ ~ 130 ℃.
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The information of Tetra-needle like ZnO whiskers
Tetra-needle like ZnO whiskers
Appearance:Loose white powder
Tetra-needle like ZnO whiskers description:1.High strength: T-ZnOw is of individual wurtzite clear with about no anatomy defects. It is about a affectionate of ideal clear with top automated backbone and modulus of elasticity. Its compactness backbone and modulus of elasticly accomplished 1.0×104 Mpa and 3.5×105 Mpa respectively, abutting to the abstract values.
2.Isotropic behaviour: the different three-dimensional tetra-needle like anatomy accord it isotropic reinforcing and modification effect, guaranteeing articles with isotropic automated properties, ambit homogeneity, thermal abbreviating and added characteristics.
3.Excellent calefaction resistance: Melting point of ZnO is college than 1800 ℃, and T-ZnOw can abide 1750 ℃. College than 1000℃ beneath atmospheric burden may aftereffect in anatomy accident at the aggravate tip.
4. Adjustable electric properties: ZnO is a n-type of semicondu
Applications:1. Antistatic polymer (white, top efficient, abiding and reinforcing effect, abrasion aggressive property)
2.wear-resistant and antiskidding abstracts (high-grade elastic tyres, brake, gear, elastic belt conveyer and etc. )
3. Microwave-absorption abstracts (wave-absorbing and catlike materials, electromagnetic careful abstracts and etc.)
4.Vibration and damping abstracts (structural vibration, automated damping, babble abridgement materials)
5. Toughening for ceram
Storage:In the dry preservation, carriage and accumulator according to non-dangerous goods.
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The introduction of 1-(p-Toluenesulfonyl)imidazole
We call a agreement for the amalgam of mono-6A-(1-butyl-3-imidazolium)-6A-deoxy--cyclodextrin chloride (BIMCD), a cationic, water-soluble cyclodextrin acclimated in the chiral break of amino acids and anionic pharmaceuticals by capillary electrophoresis. Starting from commercially accessible chemicals, BIMCD is actinic in 5 steps. The aboriginal footfall involves a nucleophilic barter amid p-toluenesulfonyl chloride and imidazole to allow 1-(p-toluenesulfonyl)imidazole (A). In the additional step, a nucleophilic barter amid -cyclodextrin and A affords mono-6A-(p-toluenesulfonyl)-6A-deoxy--cyclodextrin (B). In the third step, a nucleophilic barter amid 1-bromobutane and imidazole affords 1-butylimidazole (C). In the fourth step, a nucleophilic accession amid A and C affords BIMCD tosylate. In the final step, anion barter application an ion-exchange adhesive yields BIMCD as a awful water-soluble solid. Each footfall takes up to 2 d, including the time appropriate for artefact purification. The all-embracing agreement requires about 6 d.Appearance:White or fair powder
Packing:25 grams, 100 grams, 500 grams / bottle; 1 kg / bag; 25 kg / barrel
1-(p-Toluenesulfonyl)imidazole is a coupling reagent in oligonucleotide synthesis, reagent for careful tosylation or absolute epoxidation of diols.Chemical Name:Tosylimidazole
CAS:2232-08-8
Synonyms:1-Tosylimidazole; 1-(p-Toluenesulfonyl)-1H-imidazole; 1-[(4-methylbenzene)sulfonyl]-1H-imidazole; 1-[(4-methylphenyl)sulfonyl]-1H-imidazole; p-Toluenesulfonic acerbic imidazolide
Molecular Formula:C10H10N2O2S
Molecular Weight:222.26
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The decription of Concentrated Antibacterial Solution for Artificial Floor
Concentrated Antibacterial Solution for Artificial Floor
【Product name】Concentrated Antibacterial Solution for Artificial Floor
【Specification Model】AT-86-D
【Chemical Composition】T-ZnOw antibacterial agent, coupling agent, dispersing agent, balance and added abetting agent
【Characteristics】1. High efficient, abiding and ample spectra of antibacteria: the antibacterial aftereffect to Escherichia coli, Staphylococcus aureuss, Salmonella aertrycke and added adverse bacilli are college than 99%; and it aswell has the anti-mildew aftereffect of 1 class
2. Heathy and safety: antibacterial agents themselves are non-toxic products.
3. Excellent possibility: add to the wear-resistant cardboard impregnation, not change the aboriginal assembly process.
【Dosage】2 w%-3 w%
【Instruction for use】 Add antibacterial abettor to biconcave cement and stirred, action as aboriginal assembly technology.
【Attention】1. Sample abstracts should be fabricated afore accumulation assembly because the cement of anniversary aggregation may be different.
2. Actuality not accessory to bloom may accomplish due to the alternation amid a array of actinic abettor agents (no actuality not accessory to bloom will accomplish from accomplished products, due to the abating aftereffect of abating agent).Therefore, absolute acquaintance with physique should be abhorred during the usage, accumulator and transportation. If not anxiously splashed on derma or added locations of body, amuse bathe with water.
【Guarantee period】3 years
【Storage method】Keep in air-conditioned and dry place, and abstain of absolute sunlight.
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Monday, April 16, 2012
The description of N,N-Diisopropylethylamine
N,N-Diisopropylethylamine, or Hünig's base, DIPEA or DIEA, is an amoebic admixture and an amine. It is acclimated in amoebic allure as a base. Because the nitrogen atom is cloistral by the two isopropyl groups and an ethyl accumulation alone a proton is baby abundant to calmly fit. Just like 2,2,6,6-tetramethylpiperidine, this admixture is a acceptable abject but a poor nucleophile, which makes it a advantageous amoebic reagent. Hünig's abject is alleged afterwards the German chemist Siegfried Hünig.Hünig's abject is commercially available. It is commonly able by the acknowledgment of diisopropylamine with diethyl sulfate.Hünig's abject was advised for its use as a careful reagent in the alkylation of accessory amines to tertiary amines by alkyl halides. This amoebic acknowledgment is generally bedfast by a quaternization acknowledgment to the quaternary ammonium alkali but this side-reaction is absent if Hünig's abject is present.Hünig's abject forms a circuitous heterocyclic admixture alleged scorpionine by a acknowledgment with disulfur dichloride catalyzed by DABCO in a arresting one-pot synthesis.N, N-Diisopropylethylamine, or Hünig's base, DIPEA or DIEA, is an amoebic admixture and an amine. It is acclimated in amoebic allure as a base. Because the nitrogen atom is cloistral by the two isopropyl groups and an ethyl accumulation alone a protonis baby abundant to calmly fit. Just like 2,2,6,6-tetramethylpiperidine, this admixture is a acceptable abject but a poor nucleophile, which makes it a advantageous amoebic reagent. Hünig's abject is alleged afterwards the German chemist Siegfried Hünig.Hünig 'sbase was advised for its use as a careful reagent in the alkylation of accessory amines to tertiary amines by alkyl halides. This amoebic acknowledgment is generally bedfast by a quaternization acknowledgment to the quaternary ammonium alkali but this side-reaction is absent if Hünig's abject is present.
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Friday, April 13, 2012
The introduction of Sulforhodamine G
Sulforhodamine G is acclimated as a arctic tracer as sulforhodamine B. Compared to rhodamine B it is added fluorescent. It does not display pH-dependent assimilation or fluorescence over the ambit of 3 to 10.Similar to added sulforhodamines, the awful water-soluble sulforhodamine G can aswell be acclimated as a arctic tracer for the studies of corpuscle analysis and neuronal cell-cell communications.In our antecedent experiments, we microinjected a ambit of beaming probes (fluorescein, Lucifer chicken CH [LYCH], sulforhodamine G) into the basal trichome corpuscle to actuate symplasmic chain amid the basal trichome corpuscle and the basal covering (Fig. 1A ). As all dyes gave the aforementioned result, we present actuality abstracts for the a lot of film impermeant of these, LYCH. Given the ample numbers of PD at the e/t interface (Faulkner et al., 2008), we were afraid that in 35 of 39 injections, LYCH bootless to move beyond the e/t abuttals and access the covering (Fig. 1A). However, in anniversary injection, LYCH confused apically into added trichome beef (Fig. 1A). In all cases, cytoplasmic alive resumed anon afterwards dye injection. When dye was empiric to accept beyond the e/t barrier, alone acutely anemic fluorescence was empiric in the basal epidermal cell. In contrast, if we injected LYCH into the acknowledging epidermal cell, dye confused apically beyond the e/t abuttals into the trichome (Fig. 1B). With time (1–3 h), all dyes were cloistral boring into the axial vacuoles of the trichome cells, sulforhodamine G assuming the accomplished amount of vacuolar aloofness (data not shown).
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the information of sulfo-NHS
Product name: Sulfo-NHS
The boilerplate abstention of Thermo Scientific Pierce Sulfo-NHS is greater than 99%. Pierce Sulfo-NHS is antiseptic by a patented process, and anniversary lot is activated by quantitative NMR adjoin an centralized accepted to ensure abstention and lot-to-lot consistency. Anniversary aiguille in the NMR corresponds to a accurate proton of Sulfo-NHS, the centralized standard, or the solvents acclimated in the NMR analysis.
Chemical Name:N-Hydroxysulfosuccinimide sodium salt; Hydroxy-2,5-dioxopyrolidine-3-sulfonicacid sodium salt; Sulfo-NHS; NHSS
CAS:106627-54-7
Molecular Formula:C4H4NNaO6S
Molecular Weight:217.13
Appearance:Gray or ablaze amber powder
Packing:1g / bottle; 5g / bottle; 25g / bottle; 100g / bottle; 1 kg / bag
Product Description:sulfo-NHS is a peptide abbreviating agent, it can anatomy a abiding alive ester intermediate.
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Thursday, April 12, 2012
The description of Amylin (rat)
Pancreatic amyloid deposits, composed of the 37 amino acerbic balance peptide amylin, represent an basic allotment of blazon 2 diabetes mellitus pathology. Human amylin (hA) forms fibrils in vitro and is baneful to able pancreatic islet beta-cells. In contrast,Amylin (rat) which differs from hA by alone six amino acerbic residues in the axial arena of the peptide, residues 18-29, does not anatomy fibrils and is not cytotoxic. To annotate the role of alone residues in cilia formation, we accept generated a alternation of feature rA variants and advised their adeptness to anatomy fibrils in vitro. Single-residue substitutions with amino acids from agnate positions of the hA sequence, i.e. R18H, L23F, or V26I, were acceptable to cede rA competent for cilia accumulation admitting at a baby yield. Combining two or three of these substitutions about added the adeptness to aftermath fibrils. Variant rA cilia morphologies were advised by abrogating stain electron microscopy and begin to be agnate to those generated by hA itself. Bulk assays, i.e. involving thioflavin-T fluorescence and sedimentation, showed that the bulk of cilia accumulation was almost baby for these rA variants if compared to hA beneath the aforementioned conditions. Cilia advance was approved by time-lapse diminutive force microscopy, and MALDI-TOF accumulation spectrometry was acclimated to verify that fibrils consisted of feature peptide. Our observations affirm antecedent letters that the three proline residues play a ascendant abrogating role in cilia formation. However, their attendance is not acceptable to absolutely abate the adeptness of rA to anatomy fibrils, as anniversary of the added three active residues (i.e. R18, L23 and V26) aswell has a ascendant modulating effect.InSoluble in water. Re-hydrate the absolute canteen with at atomic 100ml of 0.1M Acetic Acerbic or any added acerb buffer. Amylin (rat) is a peptide that displays 50% affinity with calcitonin gene-related peptide (CGRP).Amylin (rat)is colocalized with somatostatin in endocrine beef of the belly fundus. In abandoned abrasion stomach. Amylin (rat) acquired a concentration-dependent abatement in acerbic secretion. In rat fundic segments. Amylin (rat) and CGRP anniversary acquired a concentration-dependent access in somatostatin and a abatement in histamine secretion.
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THE INFORMATION OF TBTU
Product name:TBTU
CAS No.125700-67-6
Molecular Formula: C11H16BF4N5O
Molecular Weight: 321.1
Appearance: White to fair powder
Purity: 99% min.
Melting Point: 200-205 oC(dec.)
Loss on Drying: ≤0.5%
Heavy Metals: ≤20ppm
NMR Spectrum 1H Consistent
Solubility 1mmole in 2 ml DMF, acutely soluble
TBTU(O-(Benzotriazol-1-yl)-N,N,N',N'-tetra methyluronium tetrafluoroborate) is acclimated as a peptide coupling reagent.
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CAS No.125700-67-6
Molecular Formula: C11H16BF4N5O
Molecular Weight: 321.1
Appearance: White to fair powder
Purity: 99% min.
Melting Point: 200-205 oC(dec.)
Loss on Drying: ≤0.5%
Heavy Metals: ≤20ppm
NMR Spectrum 1H Consistent
Solubility 1mmole in 2 ml DMF, acutely soluble
TBTU(O-(Benzotriazol-1-yl)-N,N,N',N'-tetra methyluronium tetrafluoroborate) is acclimated as a peptide coupling reagent.
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Wednesday, April 11, 2012
the information of 1-(p-Toluenesulfonyl)imidazole
Product name:1-(p-Toluenesulfonyl)imidazole
CAS Amount 2232-08-8 Empirical Formula (Hill Notation) C10H10N2O2S Molecular Weight 222.26 Beilstein Registry Amount 612451 EC Amount 218-771-9 MDL amount MFCD00005285 PubChem Substance ID 24854659
assay 99%
mp 76-78 °C(lit.)
Description
Application
Alcohols to azides in one step.1
Coupling reagent in oligonucleotide synthesis.
Packaging
5 g in bottle btl
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CAS Amount 2232-08-8 Empirical Formula (Hill Notation) C10H10N2O2S Molecular Weight 222.26 Beilstein Registry Amount 612451 EC Amount 218-771-9 MDL amount MFCD00005285 PubChem Substance ID 24854659
assay 99%
mp 76-78 °C(lit.)
Description
Application
Alcohols to azides in one step.1
Coupling reagent in oligonucleotide synthesis.
Packaging
5 g in bottle btl
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The description of 6-FAM phosphoramidite
6-FAM Phosphoramidite (FAM-amidite; FAM Phosphoramidite) is active to characterization oligonucleotides with fluorescein. It has account in apprehension of nucleotide hybridization, changes in nucleotide conformation, archetype agency bounden to DNA, archetype of siRNA addition into cells, abatement interactions amid labeled oligonucleotides with interacting bounden molecules, and quantitation of PCR amplification. FIVEphoton Biochemicals offers 6-FAM Phosphoramidite as a amount artefact in its oligonucleotide amalgam and modification reagent portfolio. CAS:204697-37-0
Molecular formula:C46H58N3O10P
Molecular weight:843.94
Description:
Storage:-20℃
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Tuesday, April 10, 2012
The Information of N,N-Diisopropylethylamine
Product name:N,N-Diisopropylethylamine
N,N-Diisopropylethylamine, or Hünig's base, DIPEA or DIEA, is an amoebic admixture and an amine. It is acclimated in amoebic allure as a base. Because the nitrogen atom is cloistral by the two isopropyl groups and an ethyl accumulation alone a proton is baby abundant to calmly fit. Just like 2,2,6,6-tetramethylpiperidine, this admixture is a acceptable abject but a poor nucleophile, which makes it a advantageous amoebic reagent. Hünig's abject is called afterwards the German chemist Siegfried Hünig.
Identifiers
CAS number: 7087-68-5
PubChem: 81531
ChemSpider:73565
EC number:230-392-0
UN number:2733
Properties
Molecular formula: C8H19N
Molar mass:129.24 g mol−1
Exact mass:129.151749613 g mol−1
Appearance:Colourless, cellophane liquid
Odor Fishy, ammoniacal
Density:742 mg mL−1
Melting point:
-273.15--50 °C, 0-223 K, -460--58 °F
Boiling point:
127 °C, 399.7 K, 260 °F
Vapor pressure: 4.1 kPa (at 37.70 °C)
Refractive basis (nD): 1.414
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The description of Amylin (rat)
Pancreatic Amylin (rat) deposits, composed of the 37 amino acerbic balance peptide amylin, represent an basic allotment of blazon 2 diabetes mellitus pathology. Human amylin (hA) forms fibrils in vitro and is baneful to able pancreatic islet beta-cells. In contrast, rat amylin (rA) which differs from hA by alone six amino acerbic residues in the axial arena of the peptide, residues 18-29, does not anatomy fibrils and is not cytotoxic. To annotate the role of alone residues in cilia formation, we accept generated a alternation of feature rA variants and advised their adeptness to anatomy fibrils in vitro. Single-residue substitutions with amino acids from agnate positions of the hA sequence, i.e. R18H, L23F, or V26I, were acceptable to cede rA competent for cilia accumulation admitting at a baby yield. Combining two or three of these substitutions about added the adeptness to aftermath fibrils. Variant rA cilia morphologies were advised by abrogating stain electron microscopy and begin to be agnate to those generated by hA itself. Bulk assays, i.e. involving thioflavin-T fluorescence and sedimentation, showed that the bulk of cilia accumulation was almost baby for these rA variants if compared to hA beneath the aforementioned conditions. Cilia advance was approved by time-lapse diminutive force microscopy, and MALDI-TOF accumulation spectrometry was acclimated to verify that fibrils consisted of feature peptide. Our observations affirm antecedent letters that the three proline residues play a ascendant abrogating role in cilia formation. However, their attendance is not acceptable to absolutely abate the adeptness of rA to anatomy fibrils, as anniversary of the added three active residues (i.e. R18, L23 and V26) aswell has a ascendant modulating effect.Amylin, aswell alleged Islet or insulinoma amyloid polypeptide (IAPP), is a 37-amino acerbic monomeric polypeptide abandoned from pancreatic amyloid, which is frequently begin in the islet of patients with diabetes mellitus blazon II and in insulinomas. Amylin is acquired from a beyond propeptide forerunner of 89 amino acids in humans. Immunostaining of amylin is begin in islet amyloid and in beef of the islets of Langherans, area it colocalizes with insulin in islet B cells.Store at -20°C. The artefact is hygroscopic and have to be adequate from light. Artefact is affirmed one year from the date of shipment. Following reconstitution, aliquot and abundance at -20°C.
Monday, April 9, 2012
the information of Tetramethylurea
Product name: Tetramethylurea
Synonyms: 1,1,3,3-Tetramethylurea; TMU
Molecular Formula :C5H12N2O
Molecular Weight :116.16
CAS Registry Number: 632-22-4
EINECS :211-173-9
Properties
Density :0.9879
Melting point: -1 ºC
Boiling point :174-178 ºC
Refractive basis :1.4496-1.4516
Flash point :65 ºC
Water solubility :miscible
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Synonyms: 1,1,3,3-Tetramethylurea; TMU
Molecular Formula :C5H12N2O
Molecular Weight :116.16
CAS Registry Number: 632-22-4
EINECS :211-173-9
Properties
Density :0.9879
Melting point: -1 ºC
Boiling point :174-178 ºC
Refractive basis :1.4496-1.4516
Flash point :65 ºC
Water solubility :miscible
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The information of Acetyl-ACTH (1-14)
The information of Acetyl-ACTH (1-14) is for analysis use only. Not for use in analytic or ameliorative procedures.For reviews on ACTH and accompanying peptides see:
D.de Wied: Pituitary Adrenal System Hormones and Behaviour. Symposium on Developments in Endocrinology (1976) / Anon.: ACTH and Accompanying Peptides: Structure, Regulation, and Action. Ann. N.Y. Acad. Sci. 297, 1 (1977) / A.V.Schally: Aspects of Hypothalamic Regulation of the Pituitary Gland. Science 202, 18 (1978) / R.Schwyzer: Studies on Polypeptide Receptors. A Critical View on the Mechanism of ACTH Action. Bull. Schweiz. Acad. Med. Wiss. 34, 263 (1978).FORMAT
Peptides are lyophilized in a solid crumb format. Peptides can be reconstituted in band-aid application the adapted absorber as needed.
STORAGE
Maintain air-conditioned at 2-8°C for up to 6 months. For continued appellation accumulator abundance at -20°C.
PRECAUTION
SSpecification:1-100mg
Sequence (three letter code):Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly
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Thursday, April 5, 2012
The description of 6-TAMRA, 6-Carboxytetramethylrhodamine
All strains grew on BAM agar containing 2 % (w/v) NaCl. Phenylalanine and tyrosine were not hydrolysed. Acid was produced from L-arabinose, ribose, D-xylose, D-galactose, D-glucose, D-fructose, D-mannose and trehalose, but not from ribitol, sorbitol, N-acetylglucosamine, L-arabitol, gluconate, 2-ketogluconate and 5-ketogluconate. All strains produced spores within several days of growth (BAM agar), with the exception of strain S-TABT, which produced only small amounts of spores after 10 days. In addition, many vegetative cells of strain S-TABT on YSG agar died within 7 days and therefore repeated subculturing was difficult using the most popular YSG medium for cultivation of Alicyclobacillus. The diameter of swollen sporangia from strain 5-A239-2O-AT was more than three times that of vegetative cells.6-TAMRA, 6-Carboxytetramethylrhodamine is a single isomer free acid which can be used for labeling free amines on proteins. TAMRA excites at 560 nm and emits at 583 nm.This single isomer amine-reactive red fluorescent derivatization reagent may be used for covalent labeling of proteins and alkylamino modified nucleic acids.
The fluorescence quantum yield of TAMRA conjugates is about one-fourth that of fluorescein conjugates. Nevertheless, TAMRA conjugates often appear brighter than the corresponding fluorescein conjugates due to the fact that TAMRA is readily excited by the 546 nm spectral line from mercury-arc lamps used in most fluorescence microscopes and is intrinsically more photostable than fluorescein. TAMRA is also efficiently excited by the 543 nm spectral line of the green He-Ne laser.
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Sunday, April 1, 2012
The description of β-Amyloid (1-40), Rat
The effect of β-Amyloid (1-40), Rat was studied in long-term potentiation of glutamatergic excitatory field potentials recorded postsynaptic molecular in the inner layer in the dentate gyrus in rats in vitro. In the presence of 200 nM β-amyloid (1-40) there was an increase in long-term potentiation of 51%. Basal synaptic transmission was not affected. These results provide direct evidence that the relatively low concentration of β-Amyloid (1-40), Rat increases synaptic plasticity.
We examined the histological changes produced by injections of beta-amyloid [β (1-40)], and control peptides in rat and monkey cerebral cortex. ß (25-35) injections were also studied in the rat cortex. Immunoperoxidase procedures standards were used to detect the distribution of tau, MAP2, β (1-40) and ALZ 50 immunoreactivity. All injections of localized necrosis at the injection site surrounded by a zone of neuronal loss and gliosis. In rat cortex, the lesions produced by solubilized β-Amyloid (1-40), Rat and β (25-35) in water were generally larger than those produced by control peptides. Tau and ALZ 50 antibodies labeled neurites and diffuse positive perikarya around β-Amyloid (1-40), Ratinjections, whereas MAP2 staining was reduced in parallel with the distribution of neuronal loss and gliosis. In the cortex of aged primates, lesion size β (1-40) was dose dependent. Hyalinized, ALZ 50 positive neurons, and abnormal neurites were prominent around the injection site. Although β-amyloid is strongly neurotoxic in the rat and monkey cerebral cortex, neuronal degeneration in primates is more similar to that found in AD.
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