Tuesday, April 17, 2012

The introduction of 1-(p-Toluenesulfonyl)imidazole


We call a agreement for the amalgam of mono-6A-(1-butyl-3-imidazolium)-6A-deoxy--cyclodextrin chloride (BIMCD), a cationic, water-soluble cyclodextrin acclimated in the chiral break of amino acids and anionic pharmaceuticals by capillary electrophoresis. Starting from commercially accessible chemicals, BIMCD is actinic in 5 steps. The aboriginal footfall involves a nucleophilic barter amid p-toluenesulfonyl chloride and imidazole to allow 1-(p-toluenesulfonyl)imidazole (A). In the additional step, a nucleophilic barter amid -cyclodextrin and A affords mono-6A-(p-toluenesulfonyl)-6A-deoxy--cyclodextrin (B). In the third step, a nucleophilic barter amid 1-bromobutane and imidazole affords 1-butylimidazole (C). In the fourth step, a nucleophilic accession amid A and C affords BIMCD tosylate. In the final step, anion barter application an ion-exchange adhesive yields BIMCD as a awful water-soluble solid. Each footfall takes up to 2 d, including the time appropriate for artefact purification. The all-embracing agreement requires about 6 d.Appearance:White or fair powder
Packing:25 grams, 100 grams, 500 grams / bottle; 1 kg / bag; 25 kg / barrel
1-(p-Toluenesulfonyl)imidazole is a coupling reagent in oligonucleotide synthesis, reagent for careful tosylation or absolute epoxidation of diols.Chemical Name:Tosylimidazole
CAS:2232-08-8
Synonyms:1-Tosylimidazole; 1-(p-Toluenesulfonyl)-1H-imidazole; 1-[(4-methylbenzene)sulfonyl]-1H-imidazole; 1-[(4-methylphenyl)sulfonyl]-1H-imidazole; p-Toluenesulfonic acerbic imidazolide
Molecular Formula:C10H10N2O2S
Molecular Weight:222.26
Read more: buy 1-(p-Toluenesulfonyl)imidazole

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