About Dexamethasone

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs.It acts as an anti-inflammatory and immunosuppressant.It is used to treat many inflammatory and autoimmune conditions, such as rheumatoid arthritis。
Dexamethasone is used in transvenous screw-in cardiac pacing leads to minimize the inflammatory response of the myocardium. The steroid is released into the myocardium as soon as the screw is extended and can play a significant role in minimizing the acute pacing threshold due to the reduction of inflammatory response. The typical quantity present in a lead tip is less than 1.0 mg.