The Characteristics of Beta Amyloid [1-40] Peptide

Beta Amyloid [1-40] Peptide production results from cleavage in the extracellular domain of APP by the beta-secretase (BACE1) , which results in the production of the APP  C-terminal fragment C99. This fragment is further cleaved by the gamma-secretase at residues 40-42 to produce beta-amyloid 40 and 42 peptides. Beta-amyloid aggregation and neuritic plaque formation are pathologic hallmarks of Alzheimer disease. Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt
Storage:Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment.
Beta Amyloid [1-40] Peptide corresponds to the rat beta-amyloid 1-40 peptide.We recommend using 100% dimethyl sulfoxide (DMSO). Alternatively, hexafluoroisopropanol (HFIP) can be used.Beta Amyloid peptides are derived from amyloid precursor protein (APP) and are thought to play a role in the development of the senile plaques associated with Alzheimer's Disease.
Beta Amyloid [1-40] Peptide is stored at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
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