what is Erythromycin ?

Erythromycin is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often prescribed for people who have an allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including Mycoplasma and legionellosis. It was first marketed by Eli Lilly and Company, and it is today commonly known as EES (erythromycin ethylsuccinate, an ester prodrug that is commonly administered). It is also occasionally used as a prokinetic agent.
Erythromycin displays bacteriostatic activity or inhibits growth of bacteria, especially at higher concentrations, but the mechanism is not fully understood. By binding to the 50s subunit of the bacterial 70s rRNA complex, protein synthesis and subsequent structure and function processes critical for life or replication are inhibited. Erythromycin interferes with aminoacyl translocation, preventing the transfer of the tRNA bound at the A site of the rRNA complex to the P site of the rRNA complex. Without this translocation, the A site remains occupied and, thus, the addition of an incoming tRNA and its attached amino acid to the nascent polypeptide chain is inhibited. This interferes with the production of functionally useful proteins, which is the basis of this antimicrobial action.
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About Bestatin

Bestatin is an inhibitor of aminopeptidases and a potent, irreversible inhibitor of LTA4 hydrolase. It inhibits the aminopeptidase activity of LTA4 hydrolase with a Ki value of 201 nM. The IC50 value for inhibition of LTB4 synthesis is approximately 10 µM.
Formal Name N-​(3R-​amino-​2S-​hydroxy-​1-​oxo-​4-​phenylbutyl)-​L-​leucine,​ monohydrochloride
CAS Number 65391-42-6
Molecular Formula C16H24N2O4 · HCl
Formula Weight 344.8
Formulation A crystalline solid
Purity ≥99%
Stability 2 years
Storage -20°C
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About Amineptine Hydrochloride

Severe acne due to amineptine was first reported in 1988 , to name a few—simultaneously in the same issue of Annales de dermatologie et de vénéréologie and in 12 March 1988 of The Lancet. A year later, Dr Martin-Ortega and colleagues in Barcelona, Spain reported a case of "acneiform eruption" in a 54-year-old woman whose intake of amineptine was described as "excessive."[13] One year after that, Vexiau and colleagues reported six women, one of whom never admitted to using amineptine, getting severe acne concentrated in the face, back and thorax, the severity of which varied with the dosage. Most of them were treated unsuccessfully with isotretinoin (Accutane) for about 18 months; two of the three that discontinued amineptine experienced a reduction in cutaneous symptoms, with the least affected patient going into remission.
This can be seen as a general side effect of central dopamine enhancement, due to the inhibitory effect of dopamine on prolactin, with the subsequent increase in testosterone output, leading in turn to the same potential for acne as is typical of pubescents.
Amineptine Hydrochloride
CAS No.:30272-08-3
Synonyms: 7-[(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)amino]heptanoic acid hydrochloride
Molecular Formula:  C22H27NO2.HCl
Molecular Weight: 373.92
Canonical SMILES: C1(c2c(CCc3c1cccc3)cccc2)[NH2+]CCCCCCC(O)=O.[ClH-]

what is Ceftriaxone ?

Ceftriaxone belongs to the family of antibiotics known as cephalosporins. It is used to prevent or treat certain infections caused by bacteria. It is given by injection only into a muscle or vein.
Ceftriaxone is often used to treat infections of the lung, urinary tract, skin, abdomen, bone, joint, and lining of the brain (meningitis), depending on the bacteria causing them. It can also be used to treat gonorrhea (a sexually transmitted infection).
Ceftriaxone is often used for the treatment of community-acquired or mild to moderate health care-associated pneumonia. It is also a choice drug for treatment of bacterial meningitis. In pediatrics, it is commonly used in febrile infants between 4 and 8 weeks of age who are admitted to the hospital to exclude sepsis. The dosage for acute ear infection in the very young is 50 mg IM, one dose daily up to three days. It has also been used in the treatment of Lyme disease, typhoid fever, and gonorrhea.
Intravenous dosages may be adjusted for body mass in younger patients and is administered every 12–24 hours, at a dose that depends on the type and severity of the infection.
For the treatment of gonorrhea, a single intramuscular injection is usually given. According to the Journal of Family Practice, Volume 60, NO 12, December 2011, the intramuscular dose of Ceftriaxone  Rocephin) has been increased from 125 mg IM to 250 mg IM due to increasing resistance of the gonococcal bacteria. It is also recommended that 100 mg of doxycycline be given orally at the same time for dual treatment. This takes care of treatment of underlying chlamydia, since treatment for chlamydia infection is also recommended. It must not be mixed or administered simultaneously (within 48 hours) with calcium-containing solutions or products for patients younger than 28 days old, even via different infusion lines .
CAS:104376-79-6
Molecular formula:C18H16N8Na2O7S3
Molecular weight:598.54

About 3Y yttria stabilized Nano-zro2 zirconium dioxide for ceramic

Product name :  3Y yttria stabilized Nano-zro2 zirconium dioxide for ceramic

CAS# : 1314-23-4

Property : small particle size of 20-40nm, 99.9% purity

Characteristic : Ceramics have good permeability and high bright cleanliness of surface when you  add 3Y yttria stabilized Nano-zirconia to it.
Use range :
1.3Y yttria stabilized Nano-zro2 zirconium dioxide for ceramic can be used on high strength, high toughness, wear-resistant products: mill lining,
cutting tools, drawing dies, hot extrusion die, nozzles, valves, ball, pump parts, a variety of sliding parts, etc.;
2. The product can be used on functional ceramics, structural ceramics, in particular, electronic ceramics,
biological ceramics (such as: denture)
3. The product can be used in refractory materials: electronic ceramic bearing plate burning, melting glass,
metallurgy and metal materials;
4. After silane modified, when nano-ZrO2 particles are in the 3.0% addition level, you can significantly
improve the nano ZrO2/PMMA composite flexural strength.

We also produce 300 tons of 5Y yttria stabilized Nano-zirconia powder and particles and 300 tons of
8Y yttria stabilized Nano-zirconia powder and particles per year.
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what is Lithium hydroxide ?

Lithium hydroxide is an inorganic compound with the formula LiOH. It is a white hygroscopic crystalline material. It is soluble in water and slightly soluble in ethanol. It is available commercially in anhydrous form and as the monohydrate (LiOH.H2O), both of which are strong bases.
Lithium hydroxide is mainly consumed for the production of lithium greases. A popular lithium grease is lithium stearate, which is a general-purpose lubricating grease due to its high resistance to water and usefulness at both high and low temperatures.
Lithium hydroxide  is used as a heat transfer medium and as a storage-battery electrolyte. It is also used in ceramics and some Portland cement formulations. Lithium hydroxide (isotopically enriched in lithium-7) is used to alkalize the reactor coolant in pressurized water reactors for corrosion control.
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Naloxone hydrochloride dihydrate

Naloxone is an narcotic antagonist structurally related to oxymorphone (methyl group on the nitrogen is replaced by allylic group). It is derived from thebaine, a minor opiate alkaloid. The chemical name of The chemical name of naloxone is (-)-17-Allyl-4, 5a-epoxy-3,14-dihydroxymorphinan-6-one. Naloxone reverse opioid-induced respiratory depression, and as an adjunct in the treatment of sedation and hypotension. Naloxone blocks the action of alpha-agonists at opioid sites. It is a competitive antagonist for mu, kappa, delta, and sigma opioid receptors. Naloxone is specifically used to in emergency opioid overdose treatment. Structurally similar naltrexone is used for the long-term dependence treatment against opioid and alcohol addiction.Naloxone hydrochloride dihydrate  is orthorhombic.
Product Categories:Opioids;Antagonists;Pharmacologicals;Enzyme Inhibitors;Enzyme Inhibitors by Type;
mp : 182 °C
storage temp:  2-8°C
solubility : ethanol: 3.3 mg/mL stable for several months refrigerated if protected from light.
form : powder
color:  white to off-white

CAS : 1481-60-85
Molecular Formula : C19H26ClNO6
Formula Weight : 399.87

what is Oxymetazoline hydrochloride

Oxymetazoline is a selective alpha-1 agonist and partial alpha-2 agonist topical decongestant, used in the form of Oxymetazoline hydrochloride .It was developed from xylometazoline at E. Merck Darmstadt by Fruhstorfer in 1961. Oxymetazoline is generally available as a nasal spray.
Oxymetazoline is available over-the-counter as a topical decongestant in the form of oxymetazoline hydrochloride in nasal sprays such as Afrin, Operil, Dristan, Dimetapp, oxyspray, Facimin, Nasivin, Sudafed OM, Vicks Sinex, Zicam, SinuFrin, and Mucinex Full Force. It was developed from xylometazoline at E. Merck Darmstadt by Fruhstorfer in 1961.
Due to its vasoconstricting properties, Oxymetazoline is also used to treat nose bleed and eye redness due to minor irritation (marketed as Visine L.R. in the form of eye drops).
Oxymetazoline hydrochloride is an adrenergic vasoconstrictor. :It is prescribed topically in the treatment of nasal congestion and for the relief of eye redness caused by minor eye irritation.
Hyperthyroidism, diabetes, use of a monoamine oxidase inhibitor within 14 days, or known hypersensitivity to this drug prohibits its use.
adverse effects: Among the more serious adverse effects are rebound congestion, central nervous system stimulation, hypertension, and transient stinging.

About Bacitracin zinc

Bacitracin zinc is a medicine applied to cuts and other skin wounds to help prevent infection. Bacitracin is a germ-killing medicine called an antibiotic. Small amounts of bacitracin zinc are dissolved in petroleum jelly to create antibiotic ointments.
Bacitracin zinc ointments are available as a salve for the eyes and for use as a topical treatment for skin problems. Bacitracin zinc falls into the category of an ophthalmic antibiotic as well as that of a topical antibiotic。
For best results with Bacitracin Zinc ointment for topical use, you will have to clean and completely dry the area on which you are going to use it. A very small amount of ointment, which when applied forms a thin layer, is more than enough. The use of more ointment does not mean a faster healing rate. You can wrap a bandage around the area. Do not let Bacitracin Zinc ointment come in contact with eyes.
To use Bacitracin Zinc ointment in the eyes, pull the bottom eyelid down so that the pink flesh is exposed and squeeze a little ointment into that area of your eye, then close your eyes for about two minutes.

CAS:92528-87-5

Specification:60iu/mg

Molecular Formula: C66H101N17O16SZn

Molecular Weight: 1486.06994628906 g/mol

Agkistrodon acutus

Agkistrodon acutus has a big head, triangle shape. There is a short and upwarp gibbosity formed by rostral and nose scales in rostral part. Head dorsal is blackish-brown, with large symmetrical scales and dimple. Its back  body is nut brown and dark brown, with a large square plaque in the middle of back. Ventral is white, with interlaced patches of dark brown. Its bodily form is short, the longest male 1335 +206 mm, females 1238 +165 mm.
It has been long said of medicinal value of Agkistrodon acutus, but as the main drug acutus, specifically for medical research of rheumatoid arthritis has not been the first time. Experts believe that Agkistrodon acutus venom has the function of expelling wind and remiving damness, anticoagulation and antithrombotic, removing fibrin, lower blood viscosity, expansion of blood vessels, improving microcirculation and reduce blood lipids. The medicinal value of Agkistrodon acutus venom is major applications in the treatment of rheumatic diseases.
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what is Esomeprazole

Esomeprazole is used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and Zollinger-Ellison syndrome. Esomeprazole is the S-enantiomer of omeprazole , and AstraZeneca claims improved efficacy of this single enantiomer product over the racemic  mixture of omeprazole. However, this greater efficacy has been disputed, with some claiming it offers no benefit from its older form. The primary uses of esomeprazole are gastroesophageal reflux disease, treatment and maintenance of erosive esophagitis, treatment of duodenal ulcers caused by H. pylori, prevention of gastric ulcers in those on chronic NSAID therapy, and treatment of gastrointestinal ulcers associated with Crohn's disease.Esomeprazole is combined with the antibiotics clarithromycin and amoxicillin (or metronidazole in penicillin-hypersensitive patients) in the 7-14 day eradication triple therapy for Helicobacter pylori. Infection by H. pylori is the causative factor in the majority of peptic and duodenal ulcers.

about Melarsomine

Melarsomine is the drug of choice for the first stage and is effective for killing adult heartworms living in the arteries of the lungs.,it is an arsenic-based drug. Although these drugs are known to kill adult heartworms, the exact method of the killing action is unknown. Melarsomine administration does not result in arsenic poisoning,it is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian.

Synonyms: Melarsominum;Arsonodithious acid
CAS No. :128470-15-5

Molecular Formula:  C₁₃H₂₁AsN₈S₂ 

Molecular Weight:  428.411

About Heparin sodium

Heparin sodium may prolong the one-stage prothrombin time. Therefore, when heparin sodium is given with dicumarol or warfarin sodium, a period of at least 5 hours after the last intravenous dose should elapse before blood is drawn if a valid PROTHROMBIN time is to be obtained.
Platelet inhibitors: Drugs such as acetylsalicylicacid, dextran, phenylbutazone, ibuprofen, indomethacin, dipyridamole, hydroxychloroquine and others that interfere with platelet aggregation reactions (the main hemostatic defense of heparinized patients) may induce bleeding and should be used with caution in patients receiving heparin sodium. Teratogenic Effects:Pregnancy Category C. Animal reproduction studies have not been conducted with heparin sodium. It is also not known whether heparin sodium can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Heparin sodium should be given to a pregnant woman only if clearly needed.

Synonym: SODIUM HEPARIN;SODIUM HEPARINATE;REVIPARIN SODIUM;PORCINE HEPARIN SODIUM;BOVINE HEPARIN SODIUM;ENOXAPARIN SODIUM;HEP, NA, BOVINE;HEP, NA, PORCINE
Cas: 9041-08-1
MF: (C12H16NS2Na3)20
Melting point: >360°C.
Appearance: white or taupe brown powder.
Solubility: Soluble in water, not soluble in ethanol, ethyl ether, acetone and benzene etc organic solvents.
Used: research on biochemistry.
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Information about Sitagliptin

Sitagliptin is an oral antihyperglycemic (antidiabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class. It was developed, and is marketed, by Merck & Co. This enzyme-inhibiting drug is used either alone or in combination with other oral antihyperglycemic agents (such as metformin or a thiazolidinedione) for treatment of diabetes mellitus type 2. The benefit of this medicine is its fewer side effects (e.g., less hypoglycemia, less weight gain) in the control of blood glucose values. While safety is its advantage, efficacy is often challenged as it is often recommended to be combined with other agents like metformin. Sitagliptin works to competitively inhibit the enzyme dipeptidyl peptidase 4 (DPP-4). This enzyme breaks down the incretins GLP-1 and GIP, gastrointestinal hormones released in response to a meal. By preventing GLP-1 and GIP inactivation, they are able to increase the secretion of insulin and suppress the release of glucagon by the alpha cells of the pancreas. This drives blood glucose levels towards normal. As the blood glucose level approaches normal, the amounts of insulin released and glucagon suppressed diminishes, thus tending to prevent an "overshoot" and subsequent low blood sugar (hypoglycemia) which is seen with some other oral hypoglycemic agents.
Sitagliptin has been shown to lower HbA1c level by about 0.7% points versus placebo. It is slightly less effective than metformin when used as a monotherapy. It does not cause weight gain and has less hypoglycemia compared to sulfonylureas. Sitagliptin is recommended as a second line drug (in combination with other drugs) after the combination of diet/exercise and metformin fails.

Use of Eptifibatide

Eptifibatide is a type of "blood thinner" used to prevent blood clotsthat can cause a heart attack or other serious blood flow problems. It is used before certain procedures used to open up the blood vessels in the heart (e.g., balloon angioplasty, coronary stent placement, percutaneous coronary intervention-PCI, coronary artery bypass graft-CABG). It is also used with other medications (e.g., nitrates, beta blockers) to stop or prevent a heart attack in people with continuing chest pain when the above procedures cannot be done. It is usually used with heparin and aspirin.Eptifibatide works by preventing platelets in the blood from sticking to each other. When platelets stick to each other, they may form blood clots that may cause a heart attack or cause the opened blood vessel in the heart to close back up.

About Vinblastine

Vinblastine is an antimicrotubule drug used to treat certain kinds of cancer, including Hodgkin's lymphoma, non-small cell lung cancer, breast cancer, head and neck cancer, and testicular cancer. It is also used to treat Langerhans cell histiocytosis. Vinblastine was traditionally obtained from Catharanthus roseus, also known as Vinca rosea, a Madagascar Periwinkle. It is generated in the plant by the joining of two alkaloids catharanthine and vindoline。Vinblastine is a component of a number of chemotherapy regimens, including ABVD for Hodgkin lymphoma. It is also used to treat histiocytosis according to the established protocols of the Histiocytosis Association. Vinblastine was first isolated by Robert Noble and Charles Thomas Beer at the University of Western Ontario from the Madagascar periwinkle plant. Vinblastine's utility as a chemotherapeutic agent was first suggested by its effect on the body when the plant was consumed in a tea. Drinking the tea led to a decreased number of white blood cells, so it was hypothesized that vinblastine might be effective against cancers of the white blood cells such as lymphoma.

Vardenafil

Vardenafil belongs to a group of medicines that delay the action of enzymes called phosphodiesterases that can interfere with erectile function. Vardenafil is used to treat men with erectile dysfunction (also called sexual impotence) because it helps to maintain an erection that is produced when the penis is stroked.

Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's.
Beyond its indications for erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation, where it may significantly increase the time from vaginal penetration to ejaculation.Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with vardenafil might provoke potentially life-threatening hypotension (low blood pressure).
Further, Vardenafil causing lengthening of the QT interval. Therefore it should not be taken by men taking other medications that affect the QT interval (such as amiodarone).

CAS NO:224785-90-4
Molecular formula:C23H32N6O4S
Molecular weight:488.604 g/mol

About Tadalafil

Tadalafil is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Tadalafil is in a class of medications called phosphodiesterase (PDE) inhibitors.
Tadalafil is a PDE5 inhibitor marketed in pill form for treating erectile dysfunction (ED) under the name Cialis, and under the name Adcirca for the treatment of pulmonary arterial hypertension. In October 2011 the U.S. Food and Drug Administration (FDA) approved Cialis for treating the signs and symptoms of benign prostatic hyperplasia (BPH) as well as a combination of BPH and erectile dysfunction (ED) when the conditions coincide. It initially was developed by the biotechnology company ICOS, and then again developed and marketed world-wide by Lilly ICOS, LLC, the joint venture of ICOS Corporation and Eli Lilly and Company. Cialis tablets, in 5 mg, 10 mg, and 20 mg doses, are yellow, film-coated, and almond-shaped. The approved dose for pulmonary arterial hypertension is 40 mg (two 20-mg tablets) once daily.
Since PDE5 inhibitors such as tadalafil may cause transiently low blood pressure (hypotension), organic nitrates should not be taken for at least 48 hours after taking the last dose of tadalafil. Using organic nitrites (such as the sex drug amyl nitrite) within this timeframe may increase the risk of life-threatening hypotension.
Since people who have taken tadalafil within the past 48 hours cannot take organic nitrates to relieve angina (such as glyceryl trinitrate spray), these patients should seek immediate medical attention if they experience anginal chest pain. In the event of a medical emergency, paramedics and medical personnel should be notified of any recent doses of tadalafil.
Tadalafil is metabolized predominantly by the hepatic CYP3A4 enzyme system. The presence of other drugs which induce this system can shorten tadalafil half-life and reduce serum levels, and hence efficacy, of the drug.

Use of Rubidium chloride

Rubidium chloride is used as a catalyst and additive in gasoline. In materials science, RbCl has been used to prepare molecular nanowires as potential precursors of nanoscale devices. In chromatography, RbCl and other univalent salts have been studied for their influence on the capillary electrophoretic separation of amino acids labeled with 3-(4-carboxybenzoyl)-quinoline-2-carboxaldehyde. RbCl is utilized in the transfection of bacteria. RbCl has been used to investigate the gating and permeability of ion channels produced by botulinum neurotoxin types A and E in membranes from cultured PC12 cells.

Grade:Biotechnology grade
CAS: 7791-11-9 
Molecular Formula: RbCl
Molecular Weight: 120.92 g/mol
Specification:25g/50g
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About Nano copper powder

Appearance
Nano copper powder with different particle sizes looks purple black to black without other colors mixed. The particle is spherical and there is no obvious agglomeration.

Application
1. Surface Conductive Coating Processing of Metal and Non-metal
With a highly activated surface, nano copper powder can be used for coating under anaerobic conditions below the smelting point of the particles. This technology can be applied to the production of microelectronic devices.
2. Efficacious Catalyzer
Catalyzer made of nanopowder of copper and its alloy has high efficiency and can be used in reactions like carbon dioxide and hydrogen synthesizing methanol.
3. Conductive Paste
Copper nanoparticles can be used to replace the precious metals to make electric paste, which can significantly reduce cost. This technology can promote further optimization of the microelectronics processes.
4. Raw Materials for Bulk Metallic Nanomaterials
Large bulk copper metal nano-composite structural material can be made by powder metallurgy sintering protected by inert gas.
5. Drug Additive
The nano copper powder can be used as the additive for specific drugs to treat osteoporosis, hyperostosis and other diseases.
6. Nano-metal Self-healing Agent
The copper nanoparticles can be added into the lubricating oil of metal friction pairs for various mechanical equipment to realize self healing of the worn parts, which is energy-saving. This can also increase the service life of the equipment.
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About rosuvastatin calcium

The chemical name for rosuvastatin calcium is bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino] pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid] calcium salt .
The empirical formula for rosuvastatin calcium is (C22H27FN3O6S)2Ca and the molecular weight is 1001.14. Rosuvastatin calcium is a white amorphous powder that is sparingly soluble in water and methanol, and slightly soluble in ethanol. Rosuvastatin calcium is a hydrophilic compound with a partition coefficient (octanol/water) of 0.13 at pH of 7.0.
CRESTOR is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3- methylglutaryl coenzyme A to mevalonate, a precursor of cholesterol. In vivo studies in animals, and in vitro studies in cultured animal and human cells have shown rosuvastatin to have a high uptake into, and selectivity for, action in the liver, the target organ for cholesterol lowering. In in vivo and in vitro studies, rosuvastatin produces its lipid-modifying effects in two ways. First, it increases the number of hepatic LDL receptors on the cell-surface to enhance uptake and catabolism of LDL. Second, rosuvastatin inhibits hepatic synthesis of VLDL, which reduces the total number of VLDL and LDL particles.

(S)-(-)-Perillyl alcohol

(S)-(-)-Perillyl alcohol is a monoterpene isolated from the essential oils of lavendin, peppermint, spearmint, cherries, celery seeds, and several other plants.
Synonyms: (-)-PERILLYL ALCOHOL;PERILLYL ALCOHOL, (-)-;(-)-P-MENTHA-1,8-DIENE-7-OL;(S)-4-ISOPROPENYL-1-CYCLOHEXENYLMETHANOL;(S)-P-MENTHA-1,8-DIEN-7-OL;(S)-(-)-PERILLYL ALCOHOL;(S)-PERILLYL ALCOHOL;RARECHEM AL BD 0003
density: 0.96 g/mL at 25 °C

CAS : 18457-55-1
Molecular Formula : C₁₀H₁₆O
Formula Weight : 152.23
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About Flucloxacillin sodium

Flucloxacillin sodium (Floo-clox-ass-sill-in soh-dee-um) is a medicine which is used in certain types of bacterial infections.The information in this Medicine Guide for flucloxacillin sodium varies according to the condition being treated and the particular preparation used.

Flucloxacillin sodium belongs to a class of medicines called penicillinantibiotics. Flucloxacillin sodium is used to treat certain types of bacterial infections. It may also be used to prevent infections that may occur after carrying out surgical procedures. Flucloxacillin sodium works by killing certain types of bacteria.

CAS:1847-24-1
Molecular formula:C19H16ClFN3O5SNa
Molecular weight:475.85

About Thiabendazole

Thiabendazole is a fungicide and parasiticide.It is used primarily to control mold, blight, and other fungally caused diseases in fruits (e.g. oranges) and vegetables; it is also used as a prophylactic treatment for Dutch elm disease.
Use in treatment of aspergillosis has been reported.
As an antiparasitic, it is able to control roundworms (such as those causing strongyloidiasis) hookworms, and other helminth species which attack wild animals, livestock and humans.
Genes responsible for the maintenance of cell walls in yeast have been shown to be responsible for angiogenesis in vertebrates.Thiabendazole serves to block angiogenesis in both frog embryos and human cells. It has also been shown to serve as a vascular disrupting agent to reduce newly established blood vessels. Tiabendazole has been shown to effectively do this in certain cancer cells

About Vardenafil

Vardenafil belongs to a group of medicines that delay the action of enzymes called phosphodiesterases that can interfere with erectile function. Vardenafil is used to treat men with erectile dysfunction (also called sexual impotence) because it helps to maintain an erection that is produced when the penis is stroked.

CAS NO:224785-90-4
Molecular formula:C23H32N6O4S
Molecular weight:488.604 g/mol:

About Tadalafil

How does Tadalafil work?
Penile erection during a sexual stimulation is caused by increased blood flow into the penile arteries. To ensure increased blood flow the muscles should be relaxed. A compound called as cGMP enables this relaxation. An enzyme called phosphodiesterase type 5 (PDE5) prevents the synthesis of cGMP, thereby not allowing the muscles to smoothen and relax, which results in erectile dysfunction. Tadalafil acts on this enzyme and inhibits its action; thereby enabling the synthesis of cGMP and allowing increased blood supply to penile arteries. Tadalafil is approved by FDA. Due to the longer duration of action, which is up to about 36 hours, Tadalafil has earned the name as a “weekend pill”. You can order Tadalafil online through this website.
Side effects of Tadalafil
The common side effects reported during clinical trials are headache, muscle aches, back pain and congested nose. Almost all of these symptoms disappear within 48 hours.
Guidelines before taking Tadalafil
Tadalafil is a need based pill and should be taken only when you plan to indulge in sexual activity. The drug should be taken only by adult men and should not be taken by males below 18 years of age. It should not be consumed along with alcohol as it can produce some adverse effects. It can be taken along with food or on an empty stomach. However heavy food intake can slow down the action of the drug. Patients consuming nitrate-based drugs should not consume Tadalafil as the reaction between a nitrate based drug and Tadalafil can prove fatal.
What are the common dosages of Tadalafil?
Tadalafil pills are available in dosages of 5 mg, 10 mg and 20 mg tablets. Recommended dosage is 10 mg tabled prior to sexual activity, which can be increased to 20 mg or decreased to 5 mg depending on the effect of the drug on the individual.

About Enrofloxacin

Enrofloxacin is a fluoroquinolone antibiotic.It is a bactericidal agent.Enrofloxacin has demonstrated a significant post-antibiotic effect for both Gram-negative and Gram-positive bacteria and is active in both stationary and growth phases of bacterial replication. 
Enrofloxacin is a broad-spectrum bactericidal antibiotic. Although the mechanism of action is not well-understood, Enrofloxacin is effective against a broad spectrum of gram- positive and gram-negative bacteria including most species of the following: Pseudomonas aeruginosa, Klebsiella, E.coli., Enterobacter, Campylobacter, Shigella, Salmonella, Aeromonas, Haemophillus, Proteus, Yersinia, Serratia, Vibrio, Brucella, Chlamydia, Staphylocci.
Enrofloxacin is eliminated by both renal and hepatic metabolism. Animals with impaired kidney or liver function may need extra monitoring and dose adjustments to prevent excess drug accumulation.

Enrofloxacin is approved for use in dogs and cats. In dogs it may be given orally, intramuscularly or intra-venously. It is approved only for oral use in cats although there is published information regarding intramuscular use. One of the positive features of enrofloxacin is that it is well-absorbed orally and in many cases may be given once per day.

Fluroquinolones including enrofloxacin have been shown to cause articular cartilage abnormalities when the drug is given at high dose-levels. The age and breed of the patient should be considered when using enrofloxacin. Large and giant breeds may be more at risk because of a longer period of growth. Enrofloxacin has been shown to be safe in pregnant dogs and lactating dogs, however because of the problems with articular cartilage it should be avoided unless the benefits clearly outweigh the risk to the puppies. This work has not been repeated in cats.

CAS:93106-60-6
Specification:98min
Molecular Formula: C19H22FN3O3
Molecular Weight: 359.4 g/mol

About Norfloxacin

Norfloxacin is an antibiotic in a class of drugs called fluoroquinolones. It fights bacteria in the body. Norfloxacin is used to treat various bacterial infections, such as urinary tract infections, gonorrhea, and prostate infections.Norfloxacin is usually efficacious for urinary tract infections (curing rates about 90%).Norfloxacin is highly lipid-soluble, and penetrates tissues and cells very rapidly after administration, often achieving tissue concentrations that are several times higher than the concurrent serum levels.Norfloxacin is highly lipid-soluble, and penetrates tissues and cells very rapidly after administration, often achieving tissue concentrations that are several times higher than the concurrent serum levels.
Norfloxacin is used to treat bacterial infections of the urinary system in adults. It works by killing the bacteria which cause the infection.

Tyloxapol

Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction and removal of mucopurulent (containing mucus and pus) bronchopulmonary secretions, administered by inhalation through a nebulizer or with a stream of oxygen.tyloxapol also blocks plasma lipolytic activity, and thus the breakdown of triglyceride-rich lipoproteins.
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About Prostaglandin E1

Prostaglandin E1 (PGE1) known as Alprostadil ,is a prostaglandin. It is a drug used in the treatment of erectile dysfunction and has vasodilatory properties. In healthy humans, Prostaglandin E1 is biosynthesized "on demand" at its intended site of action from Dihomo-γ-linolenic_acid.
Alprostadil is also used in maintaining a patent ductus arteriosus in newborns. This is primarily useful when there is threat of premature closure of the ductus arteriosus in an infant with ductal-dependent congenital heart disease, including cyanotic lesions  and acyanotic lesions (e.g., coarctation of the aorta, hypoplastic left heart syndrome, critical aortic stenosis, interrupted aortic arch).
Alprostadil is sold in the United States as urethral suppositories and in injectable form. The suppositories are sold under the brand name MUSE. The injectable forms are Edex and Caverject Muse delivers alprostadil as a penile suppository, inserted into the urethra, at least ten minutes before the erection will be needed.
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Thrombin protein

Purity is determined by SDS-PAGE analysis. Thrombin is an active enzyme in the earliest steps of the blood clot formation, generated from its circulating inactive precursor prothrombin. Thrombin is a glycoprotein formed by two peptides chains of 36 and 259 amino acids linked by disulfure bonds. Three important sites have been identified on the surface of the enzyme: The catalytic site that confers to the molecule its serine protease activity, the exosite one responsible for the binding of the substrate (fibrinogen or thrombin receptor) and the exosite two responsible for the binding of antithrombin III and inactivation of Thrombin . The molecular mass of thrombin is 37 kDa.
Storage:Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles

Application:FuncS, Use at an assay dependent dilution. Specific activity, ~3800 NIH units/mg Note,activity is measured in a thrombin specific clotting assay, and compared to standardized NIH thrombin.

m-Enterococcus Agar

m-Enterococcus Agar is used for the selective isolation and enumeration of enterococci by membrane filtration.m-Enterococcus Agar is recommended for the detection of fecal streptococci using the membrane filtration technique for water testing.The food industry also has applications for testing enterococci using m-Enterococcus Agar.
m-Enterococcus Agar  is an improved agar which was found to be superior in the isolation, selectivity and enumeration of enterococci found in heavily polluted waters. Using m-Enterococcus Agar, higher counts for enterococci were obtained when compared to the standard MPN procedures. The addition of 0.2% sodium carbonate and 0.05% Tween 80 to this medium gave better results than 15 other culture media used for the direct plating of Enterococcus.

Graphite oxide

Graphite oxide, formerly called graphitic oxide or graphitic acid, is a compound of carbon, oxygen, and hydrogen in variable ratios, obtained by treating graphite with strong oxidizers. The maximally oxidized bulk product is a yellow solid with C:O ratio between 2.1 and 2.9, that retains the layer structure of graphite but with a much larger and irregular spacing.
The bulk material disperses in basic solutions to yield monomolecular sheets, known as graphene oxide by analogy to graphene, the single-layer form of graphite. Graphene oxide sheets have been used to prepare a strong paper-like material, and have recently attracted substantial interest as a possible intermediate for the manufacture of graphene. However, this goal remained elusive until 2012 since graphene obtained by this route still has many chemical and structural defects.
Graphite oxide has attracted much interest recently as a possible route for the large-scale production and manipulation of graphene, a material with extraordinary electronic properties. Graphite oxide itself is an insulator,almost a semiconductor, with differential conductivity between 1 and 5×10−3 S/cm at a bias voltage of 10 V. However, being hydrophilic, graphite oxide disperses readily in water, breaking up into macroscopic flakes, mostly one layer thick. Chemical reduction of these flakes would yield a suspension of graphene flakes. It was argued that the first experimental observation of graphene was reported by Hanns-Peter Boehm in 1962. In this early work the existence of monolayer reduced graphene oxide flakes was demonstrated. The contribution of Boehm was recently acknowledged by Andre Geim, the Nobel Prize winner for graphene research.

About ZSM-5

ZSM-5, Zeolite Socony Mobil–5, is an aluminosilicate zeolite belonging to the pentasil family of zeolites. Its chemical formula is NanAlnSi96–nO192·16H2O (0<n<27). Patented by Mobil Oil Company in 1975, it is widely used in the petroleum industry as a heterogeneous catalyst for hydrocarbon isomerization reactions.

ZSM-5  has a high silicon to aluminum ratio. Whenever an Al3+ cation replaces a Si4+ cation, an additional positive charge is required to keep the material charge-neutral. With proton (H+) as the cation, the material becomes very acidic. Thus the acidity is proportional to the Al content. The very regular 3-D structure and the acidity of ZSM-5 can be utilized for acid-catalyzed reactions such as hydrocarbon isomerization and the alkylation of hydrocarbons. One such reaction is the isomerization of meta-xylene to para-xylene. Within the pores of the ZSM-5 zeolite, para-xylene has a much higher diffusion coefficient than meta-xylene. When the isomerization reaction is allowed to occur within the pores of ZSM-5, para-xylene is able to traverse along the pores of the zeolite, diffusing out of the catalyst very quickly. This size-selectivity allows the isomerization reaction to occur quickly in high yield.

ZSM-5 has been used as a support material for catalysis. In one such example, copper is deposited on the zeolite and a stream of ethanol is passed through at temperatures of 240 to 320 °C as a vapour stream, which causes the ethanol to oxidize to acetaldehyde; two hydrogens are lost by the ethanol as hydrogen gas. It appears that the specific pore size of ZSM-5 is of benefit to this process, which also functions for other alcohols and oxidations. The copper is occasionally combined with other metals, such as chromium, to fine tune the diversity and specificity of the products, as there is likely to be more than one. Acetic acid is an example of one possible byproduct from hot copper oxidation.

Tetramisole hydrochloride

Tetramisole hydrochloride is white to off-white crystalline powder, used as an anthelmintic in the treatment of many nematodes particularly in veterinary applications. Tetramisole is a racemic mixture. The levo-form, levamisole is more active.
CAS No.:5086-74-8
Synonyms: Levamisole hydrochloride; DL-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride
Molecular Formula:  C11H12N2S.HCl 
Molecular Weight:  240.75

4-Bromo-O-phenylenediamine

Product name:4-Bromo-O-phenylenediamine
CAS:1575-37-7
Molecular Formula:C6H7BrN2
Formula Weight:     187.04
Description:
Melting point:65-69 °C (dec.)(lit.)
Boiling point:289.3 °C at 760 mmHg
Flash Point:128.8 °C
Density:1.697 g/cm3
Chemical property:White powder.
Assay: >97%
Use:Serve as medicine intermediate.
Product Categories:Amines;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het

6-Chloropurine

Formula: C5H3ClN4

Molecular weight: 154.557
IUPAC Standard InChI:
InChI=1S/C5H3ClN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10)
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IUPAC Standard InChIKey: ZKBQDFAWXLTYKS-UHFFFAOYSA-N
CAS Registry Number: 87-42-3
Chemical structure: 
This structure is also available as a 2d Mol file or as a computed 3d SD file
The 3d structure may be viewed using Java or Javascript.
Other names: 1H-Purine, 6-chloro-; Purine, 6-chloro-; 6-Chloro-9H-purine; SK 6048; X 47; 6-CP; 6-Chlorpurine; ClP; NSC 744; 6-Chloro-1H-purine

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About Colistin sulfate

Colistin (polymyxin E) is a polymyxin antibiotic produced by certain strains of Bacillus polymyxa var. colistinus. Colistin is a mixture of cyclic polypeptides colistin A and B. Colistin is effective against most Gram-negative bacilli and is used as a polypeptide antibiotic.
Colistin is a decades-old drug that fell out of favor due to its nephrotoxicity.

Colistin sulfate and colistimethate sodium may both be given intravenously, but the dosing is complicated. The very different labeling of the parenteral products of colistin methanesulfonate in different parts of the world was first revealed by Li et al.  Colistimethate sodium manufactured by Xellia (Colomycin injection) is prescribed in international units, but colistimethate sodium manufactured by Parkdale Pharmaceuticals (Coly-Mycin M Parenteral) is prescribed in milligrams of colistin base:
Colomycin 1,000,000 units is 80 mg colistimethate;
Coly-mycin M 150 mg "colistin base" is 360 mg colistimethate or 4,500,000 units.
Because colistin was introduced into clinical practice over 50 years ago, it was never subject to the regulations that modern drugs are subject to, and therefore there is no standardised dosing of colistin and no detailed trials on pharmacology or pharmacokinetics: The optimal dosing of colistin for most infections is therefore unknown. Colomycin has a recommended intravenous dose of 1 to 2 million units three times daily for patients weighing 60 kg or more with normal renal function. Coly-Mycin has a recommended dose of 2.5 to 5 mg/kg colistin base a day, which is equivalent to 6 to 12 mg/kg colistimethate sodium per day. For a 60 kg man, therefore, the recommended dose for Colomycin is 240 to 480 mg of colistimethate sodium, yet the recommended dose for Coly-Mycin is 360 to 720 mg of colistimethate sodium. Likewise, the recommended "maximum" dose for each preparation is different (480 mg for Colomycin and 720 mg for Coly-Mycin). Each country has different generic preparations of colistin, and the recommended dose will depend on the manufacturer. This complete absence of any regulation or standardisation of dose makes intravenous colistin dosing difficult for any physician.

About Nicotinamide Riboside

Nicotinamide Riboside is a natural ingredient that is found in milk. It is actually related to niacin and other forms of vitamin B3. This molecule has become more and more popular today because of various scientific studies that prove its ability to prevent obesity by helping you fight weight gain. Researchers have found that this molecule can serve as a unique supplement that will boost one’s metabolism to help burn off more calories and prevent weight gain. Apart from preventing weight gain, it also helps boost muscle performance, increase energy expenditure, and minimize the risk factors of diabetes. What makes this milk ingredient even more appealing is that it does not have any side effects.Basically, Nicotinamide Riboside is a naturally occurring precursor of NAD+. What NAD does it is allows sugars, proteins, and fats to be converted into energy. Thus, this process simply shows that nicotinamide riboside boosts NAD levels in the cells of mammals to burn sugars, proteins, and fats as energy to encourage weight loss. In order to further study the many health benefits of nicotinamide riboside (NR), Dr. Suave invented a straightforward methodology to synthesize NR so that it could be studied on a much larger scale. This method of synthezization is patented by Cornell’s Center for Technology Enterprise and Commercialization and is licensed to ChromaDex Corportation.

About Thiabendazole

Thiabendazole is a systemic benzimidazole fungicide used to control fruit and vegetable diseases such as mold, rot, blight and stain. Thiabendazole is a drug used for the treatment of infections caused by parasites (mites and worms) and fungi (molds and yeasts).Thiabendazole is a General Use Pesticide.
USE :It is used primarily to control mold, blight, and other fungally caused diseases in fruits (e.g. oranges) and vegetables; it is also used as a prophylactic treatment for Dutch elm disease.

Use in treatment of aspergillosis has been reported.
As an antiparasitic, Thiabendazole  is able to control roundworms (such as those causing strongyloidiasis), hookworms, and other helminth species which attack wild animals, livestock and humans.
Medicinally, thiabendazole is also a chelating agent, which means that it is used medicinally to bind metals in cases of metal poisoning, such as lead, mercury or antimony poisoning.

Betamethasone dipropionate

Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities. It is applied as a topical cream, ointment, lotion or gel (Diprolene) to treat itching and other minor skin conditions such as eczema.
Brand names include Alphatrex, Beta-Val, Diprolene, Diprolene AF, Diprosone, and Luxiq.
Minor side effects include dry skin and mild, temporary stinging when applied.

About Budesonide

Budesonide is a glucocorticoid steroid for the treatment of asthma, COPD and non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis. In addition, it is used for Crohn's disease (inflammatory bowel disease).
Budesonide is nebulized for maintenance and prophylactic treatment of asthma including patients who require oral corticosteroids and those who may benefit from systemic dose reduction.
Treatment of active Crohn's disease involving the ileum and/or ascending colon; maintenance of remission (for up to 3 months) of Crohn's disease (mild-to-moderate) involving the ileum and/or ascending colon.
Budesonide is contraindicated as a primary treatment of status asthmaticus or other acute episode of asthma where intensive measures are required. It is also contraindicated for patients who have hypersensitivity to budesonide.

About Desoximetasone

Desoximetasone is a medication belonging to the family of medications known as topical corticosteroids. It is used for the relief of various skin conditions, including rashes. It helps to reduce redness, itching, and irritation.Desoximetasone is a synthetic corticosteroid, a class of primarily synthetic steroids used as anti-inflammatory and anti-pruritic agents.

When using desoximetasone, some of the medication may be absorbed through the skin and into the bloodstream. Too much absorption can lead to unwanted side effects elsewhere in the body. To keep this problem to a minimum, avoid using large amounts of Desoximetasone  ver large areas, do not use it for extended periods of time, and do not cover it with airtight dressings such as plastic wrap or adhesive bandages unless specifically told to by your doctor. Children may absorb more medication than adults do. Desoximetasone is for use only on the skin and should be kept out of the eyes.
Desoximetasone can also be used to treat some types of psoriasis.

About Deflazacort

Deflazacort is a glucocorticoid used as an anti-inflammatory and immunosuppressant.
Deflazacort is an inactive prodrug which is metabolized rapidly to the active drug 21-desacetyldeflazacort.Its potency is around 70–90% that of prednisone.
CAS: 14484-47-0
Molecular formula: C25H31NO6Molecular weight: 441.523Specifications: ≥ 98%