Bestatin is an inhibitor of aminopeptidases and a potent, irreversible inhibitor of LTA4 hydrolase. It inhibits the aminopeptidase activity of LTA4 hydrolase with a Ki value of 201 nM. The IC50 value for inhibition of LTB4 synthesis is approximately 10 µM.
Formal Name N-(3R-amino-2S-hydroxy-1-oxo-4-phenylbutyl)-L-leucine, monohydrochloride
CAS Number 65391-42-6
Molecular Formula C16H24N2O4 · HCl
Formula Weight 344.8
Formulation A crystalline solid
Purity ≥99%
Stability 2 years
Storage -20°C
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Bestatin
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