Friday, December 27, 2013

what is Oxymetazoline hydrochloride


Oxymetazoline is a selective alpha-1 agonist and partial alpha-2 agonist topical decongestant, used in the form of Oxymetazoline hydrochloride .It was developed from xylometazoline at E. Merck Darmstadt by Fruhstorfer in 1961. Oxymetazoline is generally available as a nasal spray.
Oxymetazoline is available over-the-counter as a topical decongestant in the form of oxymetazoline hydrochloride in nasal sprays such as Afrin, Operil, Dristan, Dimetapp, oxyspray, Facimin, Nasivin, Sudafed OM, Vicks Sinex, Zicam, SinuFrin, and Mucinex Full Force. It was developed from xylometazoline at E. Merck Darmstadt by Fruhstorfer in 1961.
Due to its vasoconstricting properties, Oxymetazoline is also used to treat nose bleed and eye redness due to minor irritation (marketed as Visine L.R. in the form of eye drops).
Oxymetazoline hydrochloride is an adrenergic vasoconstrictor. :It is prescribed topically in the treatment of nasal congestion and for the relief of eye redness caused by minor eye irritation.
Hyperthyroidism, diabetes, use of a monoamine oxidase inhibitor within 14 days, or known hypersensitivity to this drug prohibits its use.
adverse effects: Among the more serious adverse effects are rebound congestion, central nervous system stimulation, hypertension, and transient stinging.

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